PDB entry 5vzw

View 5vzw on RCSB PDB site
Description: TRIM23 RING domain in complex with UbcH5-Ub
Class: transferase/protein binding
Keywords: RING domain, E3 ligase, TRANSFERASE-PROTEIN BINDING complex
Deposited on 2017-05-29, released 2017-08-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-09-20, with a file datestamp of 2017-09-15.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2D2, PUBC1, UBC4, UBC5B, UBCH4, UBCH5B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62837 (Start-146)
      • engineered mutation (21)
      • engineered mutation (84)
    Domains in SCOPe 2.07: d5vzwa_
  • Chain 'B':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: Homo sapiens [TaxId:9606]
    Gene: UBE2D2, PUBC1, UBC4, UBC5B, UBCH4, UBCH5B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62837 (Start-146)
      • engineered mutation (21)
      • engineered mutation (84)
    Domains in SCOPe 2.07: d5vzwb_
  • Chain 'C':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (3-78)
      • expression tag (1-2)
    Domains in SCOPe 2.07: d5vzwc1, d5vzwc2
  • Chain 'D':
    Compound: Ubiquitin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG47 (3-78)
      • expression tag (2)
    Domains in SCOPe 2.07: d5vzwd1, d5vzwd2
  • Chain 'F':
    Compound: E3 ubiquitin-protein ligase TRIM23
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM23, ARD1, ARFD1, RNF46
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: E3 ubiquitin-protein ligase TRIM23
    Species: Homo sapiens [TaxId:9606]
    Gene: TRIM23, ARD1, ARFD1, RNF46
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5vzwA (A:)
    malkrihkelndlardppaqcragpvgddmfhwqatimgpndspyqggvffltihfptdy
    pfkppkvafttriyhpninsngsikldilrsqwspaltiskvllsicsllcdpnpddplv
    peiariyktdrekynriarewtqkyam
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vzwA (A:)
    alkrihkelndlardppaqcragpvgddmfhwqatimgpndspyqggvffltihfptdyp
    fkppkvafttriyhpninsngsikldilrsqwspaltiskvllsicsllcdpnpddplvp
    eiariyktdrekynriarewtqkyam
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5vzwB (B:)
    malkrihkelndlardppaqcragpvgddmfhwqatimgpndspyqggvffltihfptdy
    pfkppkvafttriyhpninsngsikldilrsqwspaltiskvllsicsllcdpnpddplv
    peiariyktdrekynriarewtqkyam
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vzwB (B:)
    alkrihkelndlardppaqcragpvgddmfhwqatimgpndspyqggvffltihfptdyp
    fkppkvafttriyhpninsngsikldilrsqwspaltiskvllsicsllcdpnpddplvp
    eiariyktdrekynriarewtqkyam
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5vzwC (C:)
    gshmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtls
    dyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vzwC (C:)
    shmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsd
    yniqkestlhlvlrlrgg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5vzwD (D:)
    gshmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtls
    dyniqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vzwD (D:)
    hmqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdy
    niqkestlhlvlrlrgg
    

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.