PDB entry 5vjq

View 5vjq on RCSB PDB site
Description: Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I)
Class: hydrolase/immune system
Keywords: lysozyme, hydrolase, HYDROLASE-IMMUNE SYSTEM complex
Deposited on 2017-04-19, released 2018-04-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-11, with a file datestamp of 2018-04-06.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, S52T, Y53F
    Species: Mus musculus [TaxId:10090]
    Gene: IgG Heavy Chain
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-212)
  • Chain 'B':
    Compound: HyHEL10 light chain Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-End)
    Domains in SCOPe 2.07: d5vjqb1, d5vjqb2
  • Chain 'C':
    Compound: HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, S52T, Y53F
    Species: Mus musculus [TaxId:10090]
    Gene: IgG Heavy Chain
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-212)
  • Chain 'D':
    Compound: HyHEL10 light chain Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-212)
    Domains in SCOPe 2.07: d5vjqd1, d5vjqd2
  • Chain 'E':
    Compound: HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, S52T, Y53F
    Species: Mus musculus [TaxId:10090]
    Gene: IgG Heavy Chain
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-212)
  • Chain 'F':
    Compound: HyHEL10 light chain Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-End)
    Domains in SCOPe 2.07: d5vjqf1, d5vjqf2
  • Chain 'G':
    Compound: HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, S52T, Y53F
    Species: Mus musculus [TaxId:10090]
    Gene: IgG Heavy Chain
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-End)
  • Chain 'H':
    Compound: HyHEL10 light chain Fab fragment
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5VJQ (0-End)
    Domains in SCOPe 2.07: d5vjqh1, d5vjqh2
  • Chain 'I':
    Compound: lysozyme
    Species: Anas platyrhynchos [TaxId:8839]
    Database cross-references and differences (RAF-indexed):
    • Uniprot U3J0P1 (0-128)
      • conflict (36)
      • conflict (70)
    Domains in SCOPe 2.07: d5vjqi_
  • Chain 'J':
    Compound: lysozyme
    Species: Anas platyrhynchos [TaxId:8839]
    Database cross-references and differences (RAF-indexed):
    • Uniprot U3J0P1 (0-128)
      • conflict (36)
      • conflict (70)
    Domains in SCOPe 2.07: d5vjqj_
  • Chain 'K':
    Compound: lysozyme
    Species: Anas platyrhynchos [TaxId:8839]
    Database cross-references and differences (RAF-indexed):
    • Uniprot U3J0P1 (0-End)
      • conflict (36)
    Domains in SCOPe 2.07: d5vjqk_
  • Chain 'L':
    Compound: lysozyme
    Species: Anas platyrhynchos [TaxId:8839]
    Database cross-references and differences (RAF-indexed):
    • Uniprot U3J0P1 (0-128)
      • conflict (36)
    Domains in SCOPe 2.07: d5vjql_
  • Heterogens: CL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5vjqB (B:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrne
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vjqB (B:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrn
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5vjqD (D:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrne
    

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5vjqF (F:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrne
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vjqF (F:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrn
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >5vjqH (H:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrne
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vjqH (H:)
    divltqspatlsvtpgnsvslscrasqsignnlhwyqqkshesprllikyasqsisgips
    rfsgsgsgtdftlsinsvetedfgmyfcqqsnswpytfgggtkleikradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrn
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5vjqI (I:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgktpgsknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdv
    skwirgcrl
    

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5vjqJ (J:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgktpgsknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdv
    skwirgcrl
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >5vjqK (K:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgktpgsknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdv
    skwirgcrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vjqK (K:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgktknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdvskw
    irgcr
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >5vjqL (L:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgktpgsknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdv
    skwirgcrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5vjqL (L:)
    kvysrcelaaamkrlgldnyrgyslgnwvcaanyessfntqatnrntdgstdygilqins
    rwwcddgksknacgipcsvllrsditeavrcakrivsdgngmnawvawrnrcrgtdvskw
    irgcrl