PDB entry 5vjn

View 5vjn on RCSB PDB site
Description: Crystal Structure of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae Complexed with D-2,5-Dideoxy-2,5-Imino-Altritol 1,6-Bisphosphate (D-DIAB) and Adenine
Class: transferase/transferase inhibitor
Keywords: Adenine phosphoribosyltransferase, Transition state analogue, D-2, 5-Dideoxy-2, 5-imino-altritol-1, 6-bisphosphate, D-DIAB, TRANSFERASE-TRANSFERASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2017-04-19, released 2017-12-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenine phosphoribosyltransferase 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: APT1, YML022W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5vjna_
  • Chain 'B':
    Compound: adenine phosphoribosyltransferase 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: APT1, YML022W
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5vjnb_
  • Heterogens: IR8, EDO, ADE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5vjnA (A:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaip
agsnviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftllna
qkealkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5vjnA (A:)
iasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevkidy
ivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaipag
snviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftll

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5vjnB (B:)
mpiasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevki
dyivglesrgflfgptlalalgvgfvpvrkagklpgecfkatyekeygsdlfeiqknaip
agsnviivddiiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftllna
qkealkk

    Sequence, based on observed residues (ATOM records): (download) 
    >5vjnB (B:)
iasyaqelklalhqypnfpsegilfedflpifrnpglfqklidafklhleeafpevkidy
ivglesrgflfgptlalalgvgfvpvrkagklpgecfkatylfeiqknaipagsnviivd
diiatggsaaaagelveqleanlleynfvmeldflkgrsklnapvftll