PDB entry 5v84

View 5v84 on RCSB PDB site
Description: CECR2 in complex with Cpd6 (6-allyl-N,2-dimethyl-7-oxo-N-(1-(1-phenylethyl)piperidin-4-yl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-4-carboxamide)
Class: Transcription/Inhibitor
Keywords: Bromodomain, SBDD, Transcription-Inhibitor complex
Deposited on 2017-03-21, released 2017-06-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-08-09, with a file datestamp of 2017-08-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cat eye syndrome critical region protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CECR2, KIAA1740
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5v84a_
  • Chain 'B':
    Compound: Cat eye syndrome critical region protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CECR2, KIAA1740
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5v84b_
  • Chain 'C':
    Compound: Cat eye syndrome critical region protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CECR2, KIAA1740
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5v84c_
  • Chain 'D':
    Compound: Cat eye syndrome critical region protein 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CECR2, KIAA1740
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5v84d_
  • Heterogens: SO4, 96V, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5v84A (A:)
mhhhhhhasdykddddkgslvprgsmreekktkdlfeldddftamykvldvvkahkdswp
flepvdesyapnyyqiikapmdissmekklngglyctkeefvndmktmfrncrkyngess
eytkmsdnlercfhrammkh

    Sequence, based on observed residues (ATOM records): (download) 
    >5v84A (A:)
dddftamykvldvvkahkdswpflepvdesyapnyyqiikapmdissmekklngglyctk
eefvndmktmfrncrkyngesseytkmsdnlercfhrammkh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5v84B (B:)
mhhhhhhasdykddddkgslvprgsmreekktkdlfeldddftamykvldvvkahkdswp
flepvdesyapnyyqiikapmdissmekklngglyctkeefvndmktmfrncrkyngess
eytkmsdnlercfhrammkh

    Sequence, based on observed residues (ATOM records): (download) 
    >5v84B (B:)
ddftamykvldvvkahkdswpflepvdesyapnyyqiikapmdissmekklngglyctke
efvndmktmfrncrkyngesseytkmsdnlercfhrammkh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5v84C (C:)
mhhhhhhasdykddddkgslvprgsmreekktkdlfeldddftamykvldvvkahkdswp
flepvdesyapnyyqiikapmdissmekklngglyctkeefvndmktmfrncrkyngess
eytkmsdnlercfhrammkh

    Sequence, based on observed residues (ATOM records): (download) 
    >5v84C (C:)
dddftamykvldvvkahkdswpflepvdesyapnyyqiikapmdissmekklngglyctk
eefvndmktmfrncrkyngesseytkmsdnlercfhrammkh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5v84D (D:)
mhhhhhhasdykddddkgslvprgsmreekktkdlfeldddftamykvldvvkahkdswp
flepvdesyapnyyqiikapmdissmekklngglyctkeefvndmktmfrncrkyngess
eytkmsdnlercfhrammkh

    Sequence, based on observed residues (ATOM records): (download) 
    >5v84D (D:)
ddftamykvldvvkahkdswpflepvdesyapnyyqiikapmdissmekklngglyctke
efvndmktmfrncrkyngesseytkmsdnlercfhrammkh