PDB entry 5uze

View 5uze on RCSB PDB site
Description: Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P182
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: TIM barrel, IMPDH, CSGID, Structural Genomics, Center for Structural Genomics of Infectious Diseases, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex
Deposited on 2017-02-26, released 2017-03-22
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-03-22, with a file datestamp of 2017-03-17.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) [TaxId:195103]
    Gene: guaB, CPF_2558
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5uzea_
  • Chain 'B':
    Compound: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) [TaxId:195103]
    Gene: guaB, CPF_2558
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5uzeb_
  • Chain 'C':
    Compound: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) [TaxId:195103]
    Gene: guaB, CPF_2558
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5uzec_
  • Chain 'D':
    Compound: Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase
    Species: Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) [TaxId:195103]
    Gene: guaB, CPF_2558
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5uzed_
  • Heterogens: IMP, 8L1, K, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5uzeA (A:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5uzeA (A:)
ilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiamar
eggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivldt
ahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttri
vagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagcee
apgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5uzeB (B:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5uzeB (B:)
rilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiama
reggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivld
tahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttr
ivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagce
eapgaieiyqgrsykvyrgmgslgamakkfvpegvegriaykghladtiyqliggiksgm
gylgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5uzeC (C:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5uzeC (C:)
arilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiam
areggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivl
dtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsictt
rivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagc
eeapgaieiyqgrsykvyrgmgslgamavpegvegriaykghladtiyqliggiksgmgy
lgaptlenlyenanfvvqtsagfreshphdinitkeapnys

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5uzeD (D:)
snamarilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskm
aiamareggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvd
vivldtahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgs
icttrivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsi
fagceeapgaieiyqgrsykvyrgmgslgamakgssdryfqngtkkfvpegvegriaykg
hladtiyqliggiksgmgylgaptlenlyenanfvvqtsagfreshphdinitkeapnys
vnq

    Sequence, based on observed residues (ATOM records): (download) 
    >5uzeD (D:)
rilktaytfddvllvpnksevlpnevslktqltkkiqlniplmsasmdtvteskmaiama
reggigiihknmtiedqarevdrvkrsggllcgasigvtndmmervdavvkakvdvivld
tahghskgviegvkrikakypelqviagniatpeavrdlaeagadcvkvgigpgsicttr
ivagvgvpqltavmdcaeegkklgipviadgglkysgdivkalaagacaammgsifagce
eapgaieiyqgrsykvyrgmgslgamakfvpegvegriaykghladtiyqliggiksgmg
ylgaptlenlyenanfvvqtsagfreshphdinitkeapnys