PDB entry 5uwl

View 5uwl on RCSB PDB site
Description: Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-17a
Class: hydrolase/hydrolase inhibitor
Keywords: Metalloproteinase, collagenase, MMP-13, hydrolase, hydrolase-hydrolase inhibitor complex
Deposited on 2017-02-21, released 2017-07-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uwla_
  • Chain 'B':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5uwlb_
  • Heterogens: ZN, CA, 8OJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5uwlA (A:)
mynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn

    Sequence, based on observed residues (ATOM records): (download) 
    >5uwlA (A:)
tlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisfgi
kehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghslg
ldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5uwlB (B:)
mynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiad
imisfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaah
efghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedpn

    Sequence, based on observed residues (ATOM records): (download) 
    >5uwlB (B:)
prtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimisf
gikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefghs
lgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpg