PDB entry 5uvw
View 5uvw on RCSB PDB site
Description: BRD4_Bromodomain1-A1376855
Class: signaling protein/inhibitor
Keywords: Helix bundle BRD4 Bromodomain 1 - inhibitor complex three complexes per asymmetric unit, SIGNALING PROTEIN-INHIBITOR complex
Deposited on
2017-02-20, released
2017-06-21
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-06-21, with a file datestamp of
2017-06-16.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5uvwa_ - Chain 'B':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5uvwb_ - Chain 'C':
Compound: Bromodomain-containing protein 4
Species: Homo sapiens [TaxId:9606]
Gene: BRD4, HUNK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5uvwc_ - Heterogens: 8NG, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>5uvwA (A:)
krqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiiktpmdmgtikkrlen
nyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkinelp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5uvwB (B:)
krqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiiktpmdmgtikkrlen
nyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkinelp
Sequence, based on observed residues (ATOM records): (download)
>5uvwB (B:)
tnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiiktpmdmgtikkrlennyy
wnaqeciqdfntmftncyiynkpgddivlmaealeklflqkinelp
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>5uvwC (C:)
krqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiiktpmdmgtikkrlen
nyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkinelp