PDB entry 5upv
View 5upv on RCSB PDB site
Description: Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis In the presence of G36
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: IMPDH, delta CBS, Structural Genomics, Center for Structural Genomics of Infectious Diseases, CSGID, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on
2017-02-04, released
2017-02-22
The last revision prior to the SCOPe 2.06 freeze date was dated
2017-02-22, with a file datestamp of
2017-02-17.
Experiment type: XRAY
Resolution: 1.63 Å
R-factor: N/A
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: inosine-5'-monophosphate dehydrogenase
Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
Gene: guaB, guaB2, Rv3411c, MTCY78.17
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d5upva_ - Heterogens: IMP, 8KV, FMT, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5upvA (A:)
snamsrgmsgledssdlvvspyvrmgglttdpvptggddphkvamlgltfddvlllpaas
dvvpatadtssqltkkirlkvplvssamdtvtesrmaiamaraggmgvlhrnlpvaeqag
qvemvkrsggllvgaavgvggdawvrammlvdagvdvlvvdtahahnrlvldmvgklkse
vgdrvevvggnvatrsaaaalvdagadavkvgvgpgsicttrvvagvgapqitaileava
acrpagvpviadgglqysgdiakalaagastamlgsllagtaeapgelifvngkqyksyr
gmgslgamrgrggatsyskdryfaddalsedklvpegiegrvpfrgplssvihqltgglr
aamgytgsptievlqqaqfvritpaglkeshphdvamtveapnyyar
Sequence, based on observed residues (ATOM records): (download)
>5upvA (A:)
tdpvptggddphkvamlgltfddvlllpaasdvvpatadtssqltkkirlkvplvssamd
tvtesrmaiamaraggmgvlhrnlpvaeqagqvemvkrsggllvgaavgvggdawvramm
lvdagvdvlvvdtahahnrlvldmvgklksevgdrvevvggnvatrsaaaalvdagadav
kvgvgpgsicttrvvagvgapqitaileavaacrpagvpviadgglqysgdiakalaaga
stamlgsllagtaeapgelifvngkqyksyrgmgslgamrlvpegiegrvpfrgplssvi
hqltgglraamgytgsptievlqqaqfvritpaglkeshphdvamtveapny