PDB entry 5un2

View 5un2 on RCSB PDB site
Description: Crystal Structure of Mouse Cadherin-23 EC19-21 with non-syndromic deafness (DFNB12) associated mutation R2029W
Class: cell adhesion
Keywords: hearing, mechanotransduction, adhesion, calcium-binding protein, CELL ADHESION
Deposited on 2017-01-30, released 2018-02-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-09-19, with a file datestamp of 2018-09-14.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cadherin-23
    Species: Mus musculus [TaxId:10090]
    Gene: Cdh23
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99PF4 (1-End)
      • initiating methionine (0)
      • engineered mutation (75)
    Domains in SCOPe 2.08: d5un2a1, d5un2a2, d5un2a3
  • Heterogens: CA, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5un2A (A:)
mnhplftegtyqaevmenspagtpltvlngpilaldadedvyavvtyqllgthsdlfvid
nstgvvtvrsgiiidweafsppflellllaedigqlngtahlfitilddndnwptfsppt
ytvhllencppgfsvlqvtatdedsglngelvyrieagaqdrflihpvtgvirvgnatid
reeqesyrltvvatdrgtvplsgtaivtiliddindsrpeflnpiqtvsvlesaepgtii
anvtaidldlnpkleyhiisivakddtdrlvpdqedafavnintgsvmvksplnrelvat
yevtlsvidnasdlpehsvsvpnakltvnildvndnlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5un2A (A:)
mnhplftegtyqaevmenspagtpltvlngpilaldadedvyavvtyqllgthsdlfvid
nstgvvtvrsgiiidweafsppflellllaedigqlngtahlfitilddndnwptfsppt
ytvhllencppgfsvlqvtatdedsglngelvyrieagaqdrflihpvtgvirvgnatid
reeqesyrltvvatdrgtvplsgtaivtiliddindsrpeflnpiqtvsvlesaepgtii
anvtaidldlnpkleyhiisivakddtdrlvpdqedafavnintgsvmvksplnrelvat
yevtlsvidnasdlpehsvsvpnakltvnildvnd