PDB entry 5ujx

View 5ujx on RCSB PDB site
Description: Crystal structure of DHFR in 20% Isopropanol
Class: oxidoreductase
Keywords: dynamics, OXIDOREDUCTASE
Deposited on 2017-01-19, released 2017-12-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-09-12, with a file datestamp of 2018-09-07.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: dihydrofolate reductase
  Species: Escherichia coli [TaxId:562]
  Gene: folA, A4X18_04670, A5958_06030, A6803_16755, A6804_06290, A6I92_00465, A8V37_23295, A9D65_12475, A9R57_20685, AA102_14635, AC067_04030, AC789_1c00510, ACU57_16280, ACU90_27155, AGA26_05675, AKG99_14190, AM266_01265, AM270_12270, AMK83_01385, AML07_23835, AN206_21390, APT94_27185, APU18_01950, APZ14_15415, AUQ01_20785, AUS26_14425, AWF22_24845, AWG90_06875, AWH59_13130, AXE68_21355, BBZ52_00455, BHF46_08505, ECONIH1_00280, ECs0051, EL75_3711, EL79_3822, EL80_3768, GJ11_00260, GJ12_00260, HW42_03855, IY32_08385, JD73_13725, MJ49_06800, OK10_07960, OO96_05335, PU06_14795, PU21_08285, PU33_00085, SY51_00265, UC41_15235, UN86_27670, WM48_00255, WQ89_20085, WR15_01730
  Database cross-references and differences (RAF-indexed):
  • Uniprot C3TR70 (0-158)
    • engineered mutation (36)
  Domains in SCOPe 2.08: d5ujxa_
• Chain 'B':
  Compound: dihydrofolate reductase
  Species: Escherichia coli [TaxId:562]
  Gene: folA, A4X18_04670, A5958_06030, A6803_16755, A6804_06290, A6I92_00465, A8V37_23295, A9D65_12475, A9R57_20685, AA102_14635, AC067_04030, AC789_1c00510, ACU57_16280, ACU90_27155, AGA26_05675, AKG99_14190, AM266_01265, AM270_12270, AMK83_01385, AML07_23835, AN206_21390, APT94_27185, APU18_01950, APZ14_15415, AUQ01_20785, AUS26_14425, AWF22_24845, AWG90_06875, AWH59_13130, AXE68_21355, BBZ52_00455, BHF46_08505, ECONIH1_00280, ECs0051, EL75_3711, EL79_3822, EL80_3768, GJ11_00260, GJ12_00260, HW42_03855, IY32_08385, JD73_13725, MJ49_06800, OK10_07960, OO96_05335, PU06_14795, PU21_08285, PU33_00085, SY51_00265, UC41_15235, UN86_27670, WM48_00255, WQ89_20085, WR15_01730
  Database cross-references and differences (RAF-indexed):
  • Uniprot C3TR70 (0-158)
    • engineered mutation (36)
  Domains in SCOPe 2.08: d5ujxb_
• Heterogens: FOL, IPA, CA, CL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5ujxA (A:)
  misliaalavdrvigmenampwnlpadlawfkrntldkpvimgrhtwesigrplpgrkni
  ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
  gdthfpdyepddwesvfsefhdadaqnshsycfeilerr
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >5ujxB (B:)
  misliaalavdrvigmenampwnlpadlawfkrntldkpvimgrhtwesigrplpgrkni
  ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
  gdthfpdyepddwesvfsefhdadaqnshsycfeilerr