PDB entry 5uji

View 5uji on RCSB PDB site
Description: Crystal structure of human T2-Tryptophanyl-tRNA synthetase with H130R mutation
Class: ligase
Keywords: Rossmann-fold catalytic domain, anti-codon binding domain, H130R mutation, LIGASE
Deposited on 2017-01-18, released 2018-01-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 2.79 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan--tRNA ligase, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS, IFI53, WRS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23381 (0-End)
      • engineered mutation (33)
    Domains in SCOPe 2.08: d5ujia_
  • Chain 'B':
    Compound: Tryptophan--tRNA ligase, cytoplasmic
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS, IFI53, WRS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23381 (0-End)
      • engineered mutation (33)
    Domains in SCOPe 2.08: d5ujib_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ujiA (A:)
gidydklivrfgsskidkelinrieratgqrphrflrrgiffshrdmnqvldayenkkpf
ylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdltldqaysyav
enakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgifgftdsdcig
kisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvaprigypkpallh
stffpalqgaqtkmsasdpnssifltdtakqiktkvnkhafsggrdtieehrqfggncdv
dvsfmyltffledddkleqirkdytsgamltgelkkalievlqpliaehqarrkevtdei
vkefmtprklsfdfqklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5ujiA (A:)
gidydklivrfgsskidkelinrieratgqrphrflrrgiffshrdmnqvldayenkkpf
ylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdltldqaysyav
enakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgifgftdsdcig
kisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvaprigypkpallh
stffpalnssifltdtakqiktkvnkhafsggrdtieehncdvdvsfmyltffledddkl
eqirkdytsgamltgelkkalievlqpliaehqarrkevtdeivkefmtprklsfd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ujiB (B:)
gidydklivrfgsskidkelinrieratgqrphrflrrgiffshrdmnqvldayenkkpf
ylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdltldqaysyav
enakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgifgftdsdcig
kisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvaprigypkpallh
stffpalqgaqtkmsasdpnssifltdtakqiktkvnkhafsggrdtieehrqfggncdv
dvsfmyltffledddkleqirkdytsgamltgelkkalievlqpliaehqarrkevtdei
vkefmtprklsfdfqklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5ujiB (B:)
gidydklivrfgsskidkelinrieratgqrphrflrrgiffshrdmnqvldayenkkpf
ylytgrgpssamhvghlipfiftkwlqdvfnvplviqmtddekylwkdltldqaysyave
nakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgifgftdsdcigk
isfpaiqaapsfsnsfpqifrdrtiqclipcaidqdpyfrmtrdvaprigypkpallhst
ffpalqgaqtkdpnssifltdtakqiktkvnkhafsgncdvdvsfmyltffledddkleq
irkdytgamltgelkkalievlqpliaehqarrkevtdeivkefmtprklsfdf