PDB entry 5u4g
View 5u4g on RCSB PDB site
Description: Wild-type Transthyretin in complex with 2-Boronic Acid-1-[(1E)-2-(3-boronic acid)ethenyl]-4-chlorobenzene
Class: transport protein
Keywords: Boronic acids, Medicinal chemistry, stilbene, covalent ligand, TRANSPORT PROTEIN
Deposited on
2016-12-03, released
2017-09-27
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-11-27, with a file datestamp of
2019-11-22.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5u4ga_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5u4gb_ - Heterogens: 7UV, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5u4gA (A:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5u4gA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>5u4gB (B:)
mgptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglt
teeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystt
avvtnpke
Sequence, based on observed residues (ATOM records): (download)
>5u4gB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtn