PDB entry 5u0w

View 5u0w on RCSB PDB site
Description: E. coli dihydropteroate synthase complexed with 9-methylguanine
Class: transferase/transferase inhibitor
Keywords: E. coli, DHPS, complex, pterin site, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2016-11-27, released 2017-12-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-06, with a file datestamp of 2017-12-01.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydropteroate synthase
    Species: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [TaxId:199310]
    Gene: folP, c3933
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5u0wa_
  • Chain 'B':
    Compound: dihydropteroate synthase
    Species: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) [TaxId:199310]
    Gene: folP, c3933
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AC14 (2-283)
      • expression tag (1)
    Domains in SCOPe 2.07: d5u0wb1, d5u0wb2
  • Heterogens: 9MG, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5u0wA (A:)
    gsmklfaqgtsldlshphvmgilnvtpdsfsdggthnslidavkhanlminagatiidvg
    gestrpgaaevsveeelqrvipvveaiaqrfevwisvdtskpeviresakvgahiindir
    slsepgaleaaaetglpvclmhmqgnpktmqeapkyddvfaevnryfieqiarceqagia
    kekllldpgfgfgknlshnysllarlaefhhfnlpllvgmsrksmigqllnvgpserlsg
    slacaviaamqgahiirvhdvketveamrvveatlsakenkrye
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u0wA (A:)
    mklfaqgtsldlshphvmgilnvtnslidavkhanlminagatiidvggestrpgaaevs
    veeelqrvipvveaiaqrfevwisvdtskpeviresakvgahiindirslsepgaleaaa
    etglpvclmhmqgnpktmqeapkyddvfaevnryfieqiarceqagiakekllldpgfgf
    gknlshnysllarlaefhhfnlpllvgmsrksmigqllnvgpserlsgslacaviaamqg
    ahiirvhdvketveamrvveatlsakerye
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5u0wB (B:)
    gsmklfaqgtsldlshphvmgilnvtpdsfsdggthnslidavkhanlminagatiidvg
    gestrpgaaevsveeelqrvipvveaiaqrfevwisvdtskpeviresakvgahiindir
    slsepgaleaaaetglpvclmhmqgnpktmqeapkyddvfaevnryfieqiarceqagia
    kekllldpgfgfgknlshnysllarlaefhhfnlpllvgmsrksmigqllnvgpserlsg
    slacaviaamqgahiirvhdvketveamrvveatlsakenkrye
    

    Sequence, based on observed residues (ATOM records): (download)
    >5u0wB (B:)
    smklfaqgtsldlshphvmgilnvtslidavkhanlminagatiidvggestrpgaaevs
    veeelqrvipvveaiaqrfevwisvdtskpeviresakvgahiindirslsepgaleaaa
    etglpvclmhmqpkyddvfaevnryfieqiarceqagiakekllldpgfgfgknlshnys
    llarlaefhhfnlpllvgmsrksmigqllnvgpserlsgslacaviaamqgahiirvhdv
    ketveamrvveatlsakenkrye