PDB entry 5tz9

View 5tz9 on RCSB PDB site
Description: Structure of plasma kallikrein protease domain with inhibitor
Class: hydrolase
Keywords: serine protease, small molecule inhibitor, HYDROLASE
Deposited on 2016-11-21, released 2017-08-30
Made obsolete by 6o1s on 2019-03-06

The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'E':
    Compound: Plasma kallikrein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLKB1, KLK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03952
      • engineered mutation (20)
      • engineered mutation (77)
      • engineered mutation (118)
      • engineered mutation (127)
    Domains in SCOPe 2.07: d5tz9e_
  • Heterogens: 7SD, HOH

PDB Chain Sequences:

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5tz9E (E:)
ntgdnsvcttktstrivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahc
fdglplqdvwriysgilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapley
tefqkpislpskgdtstiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdy
kitqrmvcagykeggkdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkva
eymdwilektqssdgkaqmqspa

    Sequence, based on observed residues (ATOM records): (download) 
    >5tz9E (E:)
ivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
ilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapleytefqkpislpsytnc
wvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykeggkdackgd
sggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektqssd