PDB entry 5tt3

View 5tt3 on RCSB PDB site
Description: Crystal structure of the complex of Helicobacter pylori alpha-carbonic anhydrase with ethoxzolamide
Class: lyase
Keywords: alpha-carbonic anhydrase, Helicobacter pylori, zinc metalloenzyme, lyase, zinc, periplasm
Deposited on 2016-11-01, released 2017-09-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3a_
  • Chain 'B':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3b_
  • Chain 'C':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3c_
  • Chain 'D':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3d_
  • Chain 'E':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3e_
  • Chain 'F':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3f_
  • Chain 'G':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3g_
  • Chain 'H':
    Compound: Alpha-carbonic anhydrase
    Species: Helicobacter pylori (strain ATCC 700392 / 26695) [TaxId:85962]
    Gene: C694_06140
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5tt3h_
  • Heterogens: ZN, CL, EZL, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5tt3A (A:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3A (A:)
    kwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkavf
    fthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllv
    laigfeegkenpnldpilegiqnfkevaldaflpksinyyhfngsltappctegvawfvi
    eeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5tt3B (B:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3B (B:)
    kwdyknhrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkavffhtlk
    asfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllvlaigfee
    gkenpnldpilnfkevaldaflpksinyyhfngsltappctegvawfvieeplevsakql
    aeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5tt3C (C:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3C (C:)
    tkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkav
    ffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrll
    vlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltappctegva
    wfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >5tt3D (D:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3D (D:)
    wdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyakavffthht
    lkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllvlaigk
    enpnldpilegiqkkaldaflpksinyyhfngsltappctegvawfvieeplevsakqla
    epnqrpvqpdyntviikssaet
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >5tt3E (E:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3E (E:)
    kwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkavf
    fthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllv
    laigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltappctegvaw
    fvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >5tt3F (F:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3F (F:)
    wdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkavff
    thhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllvl
    aigfeegkenpnldpilegiqkevaldaflpksinyyhfngsltappctegvawfvieep
    levsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >5tt3G (G:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3G (G:)
    tkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdlqfkyaaskpkavfft
    hhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllvla
    igfeegkenpnldpilegiqkkqldaflpksinyyhfngsltappctegvawfvieeple
    vsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >5tt3H (H:)
    gidpftntkwdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkya
    askpkavffthhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhk
    dakgrllvlaigfeegkenpnldpilegiqkkqnfkevaldaflpksinyyhfngsltap
    pctegvawfvieeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tt3H (H:)
    wdyknkengphrwdklhkdfevcksgksqspiniehyyhtqdkadlqfkyaaskpkavff
    thhtlkasfeptnhinyrghdyvldnvhfhapmeflinnktrplsahfvhkdakgrllvl
    aigfeegkenpnldpilegiqkkfkevaldaflpksinyyhfngsltappctegvawfvi
    eeplevsakqlaeikkrmknspnqrpvqpdyntviikssaetr