PDB entry 5tr0

View 5tr0 on RCSB PDB site
Description: Lipoxygenase-1 (soybean) L754A mutant at 293K
Class: oxidoreductase
Keywords: lipoxygenase, hydrogen tunneling, OXIDOREDUCTASE
Deposited on 2016-10-24, released 2017-11-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Seed linoleate 13S-lipoxygenase-1
    Species: Glycine max [TaxId:3847]
    Gene: LOX1.1, LOX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08170 (Start-838)
      • see remark 999 (159)
      • engineered mutation (753)
    Domains in SCOPe 2.06: d5tr0a1, d5tr0a2
  • Chain 'B':
    Compound: Seed linoleate 13S-lipoxygenase-1
    Species: Glycine max [TaxId:3847]
    Gene: LOX1.1, LOX1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08170 (Start-838)
      • see remark 999 (159)
      • engineered mutation (753)
    Domains in SCOPe 2.06: d5tr0b1, d5tr0b2
  • Heterogens: FE2, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5tr0A (A:)
    mfsaghkikgtvvlmpknelevnpdgsavdnlnaflgrsvslqlisatkadahgkgkvgk
    dtflegintslptlgagesafnihfewdgsmgipgafyiknymqvefflksltleaisnq
    gtirfvcnswvyntklyksvriffanhtyvpsetpaplveyreeelkslrgngtgerkey
    driydydvyndlgnpdkseklarpvlggsstfpyprrgrtgrgptvtdpntekqgevfyv
    prdenlghlkskdaleigtkslsqivqpafesafdlkstpiefhsfqdvhdlyeggiklp
    rdvistiiplpvikelyrtdgqhilkfpqphvvqvsqsawmtdeefaremiagvnpcvir
    gleefppksnldpaiygdqsskitadsldldgytmdealgsrrlfmldyhdifmpyvrqi
    nqlnsaktyatrtilflredgtlkpvaielslphsagdlsaavsqvvlpakegvestiwl
    lakayvivndscyhqlmshwlnthaamepfviathrhlsvlhpiyklltphyrnnmnina
    larqslinangiiettflpskysvemssavyknwvftdqalpadlikrgvaikdpstphg
    vrlliedypyaadgleiwaaiktwvqeyvplyyardddvkndselqhwwkeavekghgdl
    kdkpwwpklqtledlvevcliiiwiasalhaavnfgqypygglimnrptasrrllpekgt
    peyeeminnhekaylrtitsklptlislsvieiasthasdevylgqrdnphwtsdskalq
    afqkfgnklkeieeklvrrnndpslqgnrlgpvqlpytllypsseegltfrgipnsisi
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tr0A (A:)
    hkikgtvvlmpknelevnnlnaflgrsvslqlisatkadahgkgkvgkdtflegintslp
    tlgagesafnihfewdgsmgipgafyiknymqvefflksltleaisnqgtirfvcnswvy
    ntklyksvriffanhtyvpsetpaplveyreeelkslrgngtgerkeydriydydvyndl
    gnpdkseklarpvlggsstfpyprrgrtgrgptvtdpntekqgevfyvprdenlghlksk
    daleigtkslsqivqpafesafdlkstpiefhsfqdvhdlyeggiklprdvistiiplpv
    ikelyrtdgqhilkfpqphvvqvsqsawmtdeefaremiagvnpcvirgleefppksnld
    paiygdqsskitadsldldgytmdealgsrrlfmldyhdifmpyvrqinqlnsaktyatr
    tilflredgtlkpvaielslphavsqvvlpakegvestiwllakayvivndscyhqlmsh
    wlnthaamepfviathrhlsvlhpiyklltphyrnnmninalarqslinangiiettflp
    skysvemssavyknwvftdqalpadlikrgvaikdpstphgvrlliedypyaadgleiwa
    aiktwvqeyvplyyardddvkndselqhwwkeavekghgdlkdkpwwpklqtledlvevc
    liiiwiasalhaavnfgqypygglimnrptasrrllpekgtpeyeeminnhekaylrtit
    sklptlislsvieiasthasdevylgqrdnphwtsdskalqafqkfgnklkeieeklvrr
    nndpslqgnrlgpvqlpytllypsseegltfrgipnsisi
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5tr0B (B:)
    mfsaghkikgtvvlmpknelevnpdgsavdnlnaflgrsvslqlisatkadahgkgkvgk
    dtflegintslptlgagesafnihfewdgsmgipgafyiknymqvefflksltleaisnq
    gtirfvcnswvyntklyksvriffanhtyvpsetpaplveyreeelkslrgngtgerkey
    driydydvyndlgnpdkseklarpvlggsstfpyprrgrtgrgptvtdpntekqgevfyv
    prdenlghlkskdaleigtkslsqivqpafesafdlkstpiefhsfqdvhdlyeggiklp
    rdvistiiplpvikelyrtdgqhilkfpqphvvqvsqsawmtdeefaremiagvnpcvir
    gleefppksnldpaiygdqsskitadsldldgytmdealgsrrlfmldyhdifmpyvrqi
    nqlnsaktyatrtilflredgtlkpvaielslphsagdlsaavsqvvlpakegvestiwl
    lakayvivndscyhqlmshwlnthaamepfviathrhlsvlhpiyklltphyrnnmnina
    larqslinangiiettflpskysvemssavyknwvftdqalpadlikrgvaikdpstphg
    vrlliedypyaadgleiwaaiktwvqeyvplyyardddvkndselqhwwkeavekghgdl
    kdkpwwpklqtledlvevcliiiwiasalhaavnfgqypygglimnrptasrrllpekgt
    peyeeminnhekaylrtitsklptlislsvieiasthasdevylgqrdnphwtsdskalq
    afqkfgnklkeieeklvrrnndpslqgnrlgpvqlpytllypsseegltfrgipnsisi
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tr0B (B:)
    hkikgtvvlmpknelevnvdnlnaflgrsvslqlisatkadahgkgkvgkdtflegints
    lptlgagesafnihfewdgsmgipgafyiknymqvefflksltleagtirfvcnswvynt
    klyksvriffanhtyvpsetpaplveyreeelkslrgngtgerkeydriydydvyndlgn
    pdkseklarpvlggsstfpyprrgrtgrgptvtdpntekqgevfyvprdenlghlkskda
    leigtkslsqivqpafesafdlkstpiefhsfqdvhdlyeggiklprdvistiiplpvik
    elyrtdgqhilkfpqphvvqvsqsawmtdeefaremiagvnpcvirgleefppksnldpa
    iygdqsskitadsldldgytmdealgsrrlfmldyhdifmpyvrqinqlnsaktyatrti
    lflredgtlkpvaielslphvsqvvlpakegvestiwllakayvivndscyhqlmshwln
    thaamepfviathrhlsvlhpiyklltphyrnnmninalarqslinangiiettflpsky
    svemssavyknwvftdqalpadlikrgvaikdpstphgvrlliedypyaadgleiwaaik
    twvqeyvplyyardddvkndselqhwwkeavekghgdlkdkpwwpklqtledlvevclii
    iwiasalhaavnfgqypygglimnrptasrrllpekgtpeyeeminnhekaylrtitskl
    ptlislsvieiasthasdevylgqrdnphwtsdskalqafqkfgnklkeieeklvrrnnd
    pslqgnrlgpvqlpytllypsseegltfrgipnsisi