PDB entry 5tlk

View 5tlk on RCSB PDB site
Description: complex between human cd27 and fab fragments of antibodies m2177 and h2191
Class: immune system
Keywords: immune system
Deposited on 2016-10-11, released 2017-02-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: m2177 light chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlka1, d5tlka2
  • Chain 'B':
    Compound: m2177 heavy chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkb_
  • Chain 'C':
    Compound: h2191 light chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkc1, d5tlkc2
  • Chain 'D':
    Compound: h2191 heavy chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkd_
  • Chain 'E':
    Compound: m2177 light chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlke1, d5tlke2
  • Chain 'F':
    Compound: m2177 heavy chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkf_
  • Chain 'G':
    Compound: h2191 light chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkg1, d5tlkg2
  • Chain 'H':
    Compound: h2191 heavy chain
    Species: Mus musculus, Homo sapiens [TaxId:10090, 9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5TLK (0-End)
    Domains in SCOPe 2.08: d5tlkh_
  • Chain 'X':
    Compound: CD27 antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: CD27, TNFRSF7
    Database cross-references and differences (RAF-indexed):
  • Chain 'Y':
    Compound: CD27 antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: CD27, TNFRSF7
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tlkA (A:)
divltqspaslavslgqratisckasqsvdyagdsymnwyqqkpgqppklliyaasnles
giparfsgsgsgtdftlnihpveeedaatyycqqsnedpytfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkA (A:)
divltqspaslavslgqratisckasqsvdyagdsymnwyqqkpgqppklliyaasnles
giparfsgsgsgtdftlnihpveeedaatyycqqsnedpytfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5tlkB (B:)
evqlqqsgpelvkpgasvkisckasgyafssswmnwvkqrpgkglewigriypgdgdtny
ngkfkgkatltadkssstaymqlssltsedsavyfcarsdyygdygfaywgqgtlvtvsa
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkB (B:)
evqlqqsgpelvkpgasvkisckasgyafssswmnwvkqrpgkglewigriypgdgdtny
ngkfkgkatltadkssstaymqlssltsedsavyfcarsdyygdygfaywgqgtlvtvsa
astkgpsvfplapstaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5tlkC (C:)
diqmtqspsslsasvgdrvtitcrasksvsegrwsfmhwyqqkpgkapklliyvasrles
gvpsrfsgsgsgtdftftisslqpediatyycqhsrelpwtfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkC (C:)
diqmtqspsslsasvgdrvtitcrasksvsegrwsfmhwyqqkpgkapklliyvasrles
gvpsrfsgsgsgtdftftisslqpediatyycqhsrelpwtfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5tlkD (D:)
evqlvesggglvkpggslrlscaasgftfssygmswirqapgkglewvsyidegggqtiy
pdsvkgrftisrdnaknslylqmnslraedtavyycarhrgnpfdywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkD (D:)
evqlvesggglvkpggslrlscaasgftfssygmswirqapgkglewvsyidegggqtiy
pdsvkgrftisrdnaknslylqmnslraedtavyycarhrgnpfdywgqgtlvtvssast
kgpsvfplapssgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5tlkE (E:)
divltqspaslavslgqratisckasqsvdyagdsymnwyqqkpgqppklliyaasnles
giparfsgsgsgtdftlnihpveeedaatyycqqsnedpytfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkE (E:)
divltqspaslavslgqratisckasqsvdyagdsymnwyqqkpgqppklliyaasnles
giparfsgsgsgtdftlnihpveeedaatyycqqsnedpytfgggtkleikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5tlkF (F:)
evqlqqsgpelvkpgasvkisckasgyafssswmnwvkqrpgkglewigriypgdgdtny
ngkfkgkatltadkssstaymqlssltsedsavyfcarsdyygdygfaywgqgtlvtvsa
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkF (F:)
evqlqqsgpelvkpgasvkisckasgyafssswmnwvkqrpgkglewigriypgdgdtny
ngkfkgkatltadkssstaymqlssltsedsavyfcarsdyygdygfaywgqgtlvtvsa
astkgpsvfplaptaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssv
vtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5tlkG (G:)
diqmtqspsslsasvgdrvtitcrasksvsegrwsfmhwyqqkpgkapklliyvasrles
gvpsrfsgsgsgtdftftisslqpediatyycqhsrelpwtfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkG (G:)
diqmtqspsslsasvgdrvtitcrasksvsegrwsfmhwyqqkpgkapklliyvasrles
gvpsrfsgsgsgtdftftisslqpediatyycqhsrelpwtfgqgtkveikrtvaapsvf
ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls
stltlskadyekhkvyacevthqglsspvtksfnr

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5tlkH (H:)
evqlvesggglvkpggslrlscaasgftfssygmswirqapgkglewvsyidegggqtiy
pdsvkgrftisrdnaknslylqmnslraedtavyycarhrgnpfdywgqgtlvtvssast
kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkschhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tlkH (H:)
evqlvesggglvkpggslrlscaasgftfssygmswirqapgkglewvsyidegggqtiy
pdsvkgrftisrdnaknslylqmnslraedtavyycarhrgnpfdywgqgtlvtvssast
kgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.