PDB entry 5tl8

View 5tl8 on RCSB PDB site
Description: Naegleria fowleri CYP51-posaconazole complex
Class: oxidoreductase
Keywords: CYP51, sterol 14alpha-demethylase, OXIDOREDUCTASE
Deposited on 2016-10-10, released 2017-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.71 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein CYP51
    Species: Naegleria fowleri [TaxId:5763]
    Gene: NF0102700
    Database cross-references and differences (RAF-indexed):
    • PDB 5TL8
    Domains in SCOPe 2.08: d5tl8a1, d5tl8a2
  • Heterogens: HEM, X2N, EDO, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tl8A (A:)
makktsskgklpprvpnlipyvgsfvsfaknpvqfiidnskkygdvftatilgkemtfln
hpkildtffkatdnelslrdvyrfmrpvfgtgvvydadstermmeqvkfvssglttarfr
vfvdifedeiahkvkelgpegtvdvaelmadliiftasrcllgdevrqylseknlgklyh
diddgisplsffypslpapkrdkarkavgeifqelldkrreehkkhperlldeskmdvvd
hlltqkykdgqeltdvhrigiliaglfagqhtssitsswtlmnvisnkkvlekvrkeqee
imgsdkvldydkvmkmdyleacmkealrmypplimimrmarkpreceqyiipkgnilvvs
psvagrctdtytnpdvfdperlterkehekfkygavpfgagrhkcigenfallqvksiis
illryfdmeyigkipdpsytslvvgpspptrmryklrkqqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tl8A (A:)
klpprvpnlipyvgsfvsfaknpvqfiidnskkygdvftatilgkemtflnhpkildtff
katdnelslrdvyrfmrpvfgtgvvydadstermmeqvkfvssglttarfrvfvdifede
iahkvkelgpegtvdvaelmadliiftasrcllgdevrqylseknlgklyhdiddgispl
sffypslpapkrdkarkavgeifqelldkrreehkkhperlldeskmdvvdhlltqkykd
gqeltdvhrigiliaglfagqhtssitsswtlmnvisnkkvlekvrkeqeeimgsdkvld
ydkvmkmdyleacmkealrmypplimimrmarkpreceqyiipkgnilvvspsvagrctd
tytnpdvfdperlterkehekfkygavpfgagrhkcigenfallqvksiisillryfdme
yigkipdpsytslvvgpspptrmryklrkq