PDB entry 5tjx

View 5tjx on RCSB PDB site
Description: Structure of human plasma kallikrein
Class: Hydrolase/Hydrolase Inhibitor
Keywords: plasma kallikrein, protease, serine, inhibitor, Hydrolase-Hydrolase Inhibitor complex
Deposited on 2016-10-05, released 2016-12-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-03-01, with a file datestamp of 2017-02-24.
Experiment type: XRAY
Resolution: 1.41 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Plasma kallikrein
    Species: Homo sapiens [TaxId:9606]
    Gene: KLKB1, KLK3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03952
      • engineered mutation (20)
      • engineered mutation (77)
      • engineered mutation (118)
      • engineered mutation (127)
    Domains in SCOPe 2.08: d5tjxa_
  • Heterogens: GBT, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5tjxA (A:)
    ntgdnsvcttktstrivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahc
    fdglplqdvwriysgilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapley
    tefqkpislpskgdtstiytncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdy
    kitqrmvcagykeggkdackgdsggplvckhngmwrlvgitswgegcarreqpgvytkva
    eymdwilektqssdgkaqmqspa
    

    Sequence, based on observed residues (ATOM records): (download)
    >5tjxA (A:)
    ivggtesswgewpwqvslqvkltaqrhlcggslighqwvltaahcfdglplqdvwriysg
    ilelsditkdtpfsqikeiiihqnykvsegnhdialiklqapleytefqkpislpstiyt
    ncwvtgwgfskekgeiqnilqkvniplvtneecqkryqdykitqrmvcagykeggkdack
    gdsggplvckhngmwrlvgitswgegcarreqpgvytkvaeymdwilektq