PDB entry 5tij

View 5tij on RCSB PDB site
Description: Structure of Human Enolase 2 with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonate (purified enantiomer)
Class: lyase/lyase inhibitor
Keywords: enolase gamma, glycolysis, neuron specific enolase, carbohydrate metabolism, LYASE-LYASE INHIBITOR complex
Deposited on 2016-10-03, released 2017-10-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2.63 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gamma-enolase
    Species: Homo sapiens [TaxId:9606]
    Gene: ENO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5tija1, d5tija2
  • Chain 'B':
    Compound: Gamma-enolase
    Species: Homo sapiens [TaxId:9606]
    Gene: ENO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5tijb1, d5tijb2
  • Heterogens: 5TX, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tijA (A:)
msiekiwareildsrgnptvevdlytakglfraavpsgastgiyealelrdgdkqrylgk
gvlkavdhinstiapalissglsvveqekldnlmleldgtenkskfganailgvslavck
agaaerelplyrhiaqlagnsdlilpvpafnvinggshagnklamqefmilpvgaesfrd
amrlgaevyhtlkgvikdkygkdatnvgdeggfapnilensealelvkeaidkagyteki
vigmdvaasefyrdgkydldfksptdpsryitgdqlgalyqdfvrdypvvsiedpfdqdd
waawskftanvgiqivgddltvtnpkrieraveekacnclllkvnqigsvteaiqackla
qengwgvmvshrsgetedtfiadlvvglctgqiktgapcrserlakynqlmrieeelgde
arfaghnfrnpsvlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tijA (A:)
siekiwareildsrgnptvevdlytakglfraavpsgastgiyealelrdgdkqrylgkg
vlkavdhinstiapalissglsvveqekldnlmleldgtenkskfganailgvslavcka
gaaerelplyrhiaqlagnsdlilpvpafnvinggshagnklamqefmilpvgaesfrda
mrlgaevyhtlkgvikdkygkdatnvgdeggfapnilensealelvkeaidkagytekiv
igmdvaasefyrdgkydldfksptdpsryitgdqlgalyqdfvrdypvvsiedpfdqddw
aawskftanvgiqivgddltvtnpkrieraveekacnclllkvnqigsvteaiqacklaq
engwgvmvshrsgetedtfiadlvvglctgqiktgapcrserlakynqlmrieeelgdea
rfaghnfrnpsvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5tijB (B:)
msiekiwareildsrgnptvevdlytakglfraavpsgastgiyealelrdgdkqrylgk
gvlkavdhinstiapalissglsvveqekldnlmleldgtenkskfganailgvslavck
agaaerelplyrhiaqlagnsdlilpvpafnvinggshagnklamqefmilpvgaesfrd
amrlgaevyhtlkgvikdkygkdatnvgdeggfapnilensealelvkeaidkagyteki
vigmdvaasefyrdgkydldfksptdpsryitgdqlgalyqdfvrdypvvsiedpfdqdd
waawskftanvgiqivgddltvtnpkrieraveekacnclllkvnqigsvteaiqackla
qengwgvmvshrsgetedtfiadlvvglctgqiktgapcrserlakynqlmrieeelgde
arfaghnfrnpsvlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tijB (B:)
siekiwareildsrgnptvevdlytakglfraavpsgastgiyealelrdgdkqrylgkg
vlkavdhinstiapalissglsvveqekldnlmleldgtenkskfganailgvslavcka
gaaerelplyrhiaqlagnsdlilpvpafnvinggshagnklamqefmilpvgaesfrda
mrlgaevyhtlkgvikdkygkdatnvgdeggfapnilensealelvkeaidkagytekiv
igmdvaasefyrdgkydldfksptdpsryitgdqlgalyqdfvrdypvvsiedpfdqddw
aawskftanvgiqivgddltvtnpkrieraveekacnclllkvnqigsvteaiqacklaq
engwgvmvshrsgetedtfiadlvvglctgqiktgapcrserlakynqlmrieeelgdea
rfaghnfrnpsvl