PDB entry 5tc6

View 5tc6 on RCSB PDB site
Description: Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with propylthio-immucillin-A
Class: transferase/transferase inhibitor
Keywords: phosphorylase, inhibitor, complex, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2016-09-14, released 2017-10-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-methyl-5'-thioadenosine phosphorylase
    Species: Homo sapiens [TaxId:9606]
    Gene: MTAP, MSAP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5tc6a_
  • Heterogens: 7A6, PO4, GOL, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5tc6A (A:)
mhhhhhhenlyfqsmasgttttavkigiiggtglddpeilegrtekyvdtpfgkpsdali
lgkiknvdcvllarhgrqhtimpskvnyqaniwalkeegcthvivttacgslreeiqpgd
iviidqfidrttmrpqsfydgshscargvchipmaepfcpktrevlietakklglrchsk
gtmvtiegprfssraesfmfrtwgadvinmttvpevvlakeagicyasiamatdydcwke
heeavsvdrvlktlkenankakslllttipqigstewsetlhnlknmaqfsvllprh

    Sequence, based on observed residues (ATOM records): (download) 
    >5tc6A (A:)
avkigiiggtglddpeilegrtekyvdtpfgkpsdalilgkiknvdcvllarhgrqhtim
pskvnyqaniwalkeegcthvivttacgslreeiqpgdiviidqfidrttmrpqsfydgs
hscargvchipmaepfcpktrevlietakklglrchskgtmvtiegprfssraesfmfrt
wgadvinmttvpevvlakeagicyasiamatdydcwkeheeavsvdrvlktlkenankak
slllttipqigstewsetlhnlknmaqfsvllp