PDB entry 5t26

View 5t26 on RCSB PDB site
Description: Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli.
Class: lyase
Keywords: Dihydrodipicolinate Synthase, Kinetics, Acetopyruvate modification, LYASE
Deposited on 2016-08-23, released 2016-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-08-23, with a file datestamp of 2017-08-18.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Escherichia coli O8 (strain IAI1) [TaxId:585034]
    Gene: dapA, ECIAI1_2529
    Database cross-references and differences (RAF-indexed):
    • Uniprot B7M7I1 (2-293)
      • expression tag (1)
    Domains in SCOPe 2.07: d5t26a1, d5t26a2
  • Chain 'B':
    Compound: 4-hydroxy-tetrahydrodipicolinate synthase
    Species: Escherichia coli O8 (strain IAI1) [TaxId:585034]
    Gene: dapA, ECIAI1_2529
    Database cross-references and differences (RAF-indexed):
    • Uniprot B7M7I1 (2-293)
      • expression tag (0-1)
    Domains in SCOPe 2.07: d5t26b1, d5t26b2
  • Heterogens: NA, TLA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5t26A (A:)
    hhmftgsivaivtpmdekgnvcraslkklidyhvasgtsaivsvgttgesatlnhdehad
    vvmmtldladgripviagtganataeaisltqrfndsgivgcltvtpyynrpsqeglyqh
    fkaiaehtdlpqilynvpsrtgcdllpetvgrlakvkniigixeatgnltrvnqikelvs
    ddfvllsgddasaldfmqlgghgvisvtanvaardmaqmcklaaeghfaearvinqrlmp
    lhnklfvepnpipvkwackelglvatdtlrlpmtpitdsgretvraalkhagll
    

    Sequence, based on observed residues (ATOM records): (download)
    >5t26A (A:)
    hmftgsivaivtpmdekgnvcraslkklidyhvasgtsaivsvgttgesatlnhdehadv
    vmmtldladgripviagtganataeaisltqrfndsgivgcltvtpyynrpsqeglyqhf
    kaiaehtdlpqilynvpsrtgcdllpetvgrlakvkniigixeatgnltrvnqikelvsd
    dfvllsgddasaldfmqlgghgvisvtanvaardmaqmcklaaeghfaearvinqrlmpl
    hnklfvepnpipvkwackelglvatdtlrlpmtpitdsgretvraalkhagll
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5t26B (B:)
    hhmftgsivaivtpmdekgnvcraslkklidyhvasgtsaivsvgttgesatlnhdehad
    vvmmtldladgripviagtganataeaisltqrfndsgivgcltvtpyynrpsqeglyqh
    fkaiaehtdlpqilynvpsrtgcdllpetvgrlakvkniigixeatgnltrvnqikelvs
    ddfvllsgddasaldfmqlgghgvisvtanvaardmaqmcklaaeghfaearvinqrlmp
    lhnklfvepnpipvkwackelglvatdtlrlpmtpitdsgretvraalkhagll