PDB entry 5t19
View 5t19 on RCSB PDB site
Description: Structure of PTP1B complexed with N-(3'-(1,1-dioxido-4-oxo-1,2,5-thiadiazolidin-2-yl)-4'-methyl-[1,1'-biphenyl]-4-yl)acetamide
Class: hydrolase
Keywords: HYDROLASE, protein tyrosine phosphatase, 5-(aryl)-1, 2, 5-thiadiazolidin-3-one-1, 1-dioxide unit
Deposited on
2016-08-18, released
2017-04-12
The last revision prior to the SCOPe 2.07 freeze date was dated
2017-04-26, with a file datestamp of
2017-04-21.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: tyrosine-protein phosphatase non-receptor type 1
Species: Homo sapiens [TaxId:9606]
Gene: PTPN1, PTP1B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d5t19a1, d5t19a2 - Heterogens: MG, 73U, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5t19A (A:)
ghmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsrik
lhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgs
lkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhytt
wpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkr
kdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed
lepppehipppprppkrilephn
Sequence, based on observed residues (ATOM records): (download)
>5t19A (A:)
ghmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsrik
lhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgs
lkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhytt
wpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkr
kdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed