PDB entry 5sqb

View 5sqb on RCSB PDB site
Description: PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with Z5010894390 - (R,R) and (S,S) isomers
Class: viral protein
Keywords: Macrodomain, ADP-ribose, SARS-CoV-2, VIRAL PROTEIN
Deposited on 2022-06-09, released 2022-07-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2022-07-06, with a file datestamp of 2022-07-01.
Experiment type: XRAY
Resolution: 1.05 Å
R-factor: N/A
AEROSPACI score: 0.77 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: non-structural protein 3
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-168)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5sqba_
  • Chain 'B':
    Compound: non-structural protein 3
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (2-168)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d5sqbb1, d5sqbb2
  • Heterogens: QO3, QOF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5sqbA (A:)
smvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnna
mqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqhe
vllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssfl

    Sequence, based on observed residues (ATOM records): (download) 
    >5sqbA (A:)
vnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnnamq
vesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqhevl
lapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssfl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5sqbB (B:)
smvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnna
mqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqhe
vllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssfl