PDB entry 5s8j

View 5s8j on RCSB PDB site
Description: XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with N01207d (space group C2)
Class: signaling protein
Keywords: SGC - Diamond I04-1 fragment screening, bromodomain, PHIP, XChemExplorer, SIGNALING PROTEIN
Deposited on 2020-12-17, released 2021-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 1.21 Å
R-factor: N/A
AEROSPACI score: 0.75 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: PH-interacting protein
  Species: Homo sapiens [TaxId:9606]
  Gene: PHIP, DCAF14, WDR11
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8WWQ0 (Start-127)
  Domains in SCOPe 2.08: d5s8ja_
• Heterogens: 54Y, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >5s8jA (A:)
  smsydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvretlea
  gnyespmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksalrfh
  krntitkr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >5s8jA (A:)
  ydiqawkkqceellnlifqcedsepfrqpvdlleypdyrdiidtpmdfatvretleagny
  espmelckdvrlifsnskaytpskrsriysmslrlsaffeehissvlsdyksalrfhkrn
  titkr