PDB entry 5r0j

View 5r0j on RCSB PDB site
Description: PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry F08, DMSO-free
Class: splicing
Keywords: FragMAX, FragMAXapp, fragment screening, RNaseH like domain, VHS like domain, U5 snRNP assembly, SPLICING
Deposited on 2020-03-30, released 2020-06-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-10, with a file datestamp of 2021-03-05.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pre-mRNA-splicing factor 8
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: PRP8, DBF3, DNA39, RNA8, SLT21, USA2, YHR165C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33334 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d5r0ja1, d5r0ja2
  • Chain 'B':
    Compound: A1 cistron-splicing factor AAR2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: AAR2, YBL074C, YBL06.06, YBL0611
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32357 (4-307)
      • conflict (160)
    Domains in SCOPe 2.08: d5r0jb1, d5r0jb2
  • Heterogens: RBJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5r0jA (A:)
gamnssnyaelfnndiklfvddtnvyrvtvhktfegnvatkaingciftlnpktghlflk
iihtsvwagqkrlsqlakwktaeevsalvrslpkeeqpkqiivtrkamldplevhmldfp
niairptelrlpfsaamsidklsdvvmkatepqmvlfniyddwldrissytafsrltlll
ralktneesakmillsdptitiksyhlwpsftdeqwitiesqmrdlilteygrkynvnis
altqteikdiilgqnika

    Sequence, based on observed residues (ATOM records): (download) 
    >5r0jA (A:)
gamnssnyaelfnndiklfvddtnvyrvtvhktfegnvatkaingciftlnpktghlflk
iihtsvwagqkrlsqlakwktaeevsalvrslpkeeqpkqiivtrkamldplevhmldfp
niairptelrlpfsaamsidklsdvvmkatepqmvlfniyddwldrissytafsrltlll
ralktneesakmillsdptitiksyhlwpsftdeqwitiesqmrdlilteygrkynv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5r0jB (B:)
gamamntvpftsapievtigidqysfnvkenqpfhgikdipighvhvihfqhadnssmry
gywfdcrmgnfyiqydpkdglykmmeerdgakfenivhnfkerqmmvsypkideddtwyn
ltefvqmdkirkivrkdenqfsyvdssmttvqenelsssssdpahslnytvinfksreai
rpghemedfldksyylntvmlqgifknssnyfgelqfaflnamffgnygsslqwhamiel
icssatvpkhmldkldeilyyqiktlpeqysdillnervwniclyssfqknslhntekim
enkypell

    Sequence, based on observed residues (ATOM records): (download) 
    >5r0jB (B:)
mntvpftsapievtigidqysfnvkenqpfhgikdipighvhvihfqhadnssmrygywf
dcrmgnfyiqydpkdglykmmeerdgakfenivhnfkerqmmvsypkideddtwynltef
vqmdkirkivrkdenqfsyvdssmttvqenelsdpahslnytvinfksreairpghemed
fldksyylntvmlqgifknssnyfgelqfaflnamffgnygsslqwhamielicssatvp
khmldkldeilyyqiktlpeqysdillnervwniclyssfqknslhntekimenkypell