PDB entry 5r09

View 5r09 on RCSB PDB site
Description: PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry B03, DMSO-free
Class: splicing
Keywords: FragMAX, FragMAXapp, fragment screening, RNaseH like domain, VHS like domain, U5 snRNP assembly, SPLICING
Deposited on 2020-03-30, released 2020-06-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-06-03, with a file datestamp of 2020-05-29.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pre-mRNA-splicing factor 8
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: PRP8, DBF3, DNA39, RNA8, SLT21, USA2, YHR165C
    Database cross-references and differences (RAF-indexed):
    • Uniprot P33334 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.07: d5r09a1, d5r09a2
  • Chain 'B':
    Compound: A1 cistron-splicing factor AAR2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: AAR2, YBL074C, YBL06.06, YBL0611
    Database cross-references and differences (RAF-indexed):
    • Uniprot P32357 (4-307)
      • conflict (160)
    Domains in SCOPe 2.07: d5r09b1, d5r09b2
  • Heterogens: SYG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5r09A (A:)
    gamnssnyaelfnndiklfvddtnvyrvtvhktfegnvatkaingciftlnpktghlflk
    iihtsvwagqkrlsqlakwktaeevsalvrslpkeeqpkqiivtrkamldplevhmldfp
    niairptelrlpfsaamsidklsdvvmkatepqmvlfniyddwldrissytafsrltlll
    ralktneesakmillsdptitiksyhlwpsftdeqwitiesqmrdlilteygrkynvnis
    altqteikdiilgqnika
    

    Sequence, based on observed residues (ATOM records): (download)
    >5r09A (A:)
    gamnssnyaelfnndiklfvddtnvyrvtvhktfegnvatkaingciftlnpktghlflk
    iihtsvwagqkrlsqlakwktaeevsalvrslpkeeqpkqiivtrkamldplevhmldfp
    niairptelrlpfsaamsidklsdvvmkatepqmvlfniyddwldrissytafsrltlll
    ralktneesakmillsdptitiksyhlwpsftdeqwitiesqmrdlilteygrkynv
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5r09B (B:)
    gamamntvpftsapievtigidqysfnvkenqpfhgikdipighvhvihfqhadnssmry
    gywfdcrmgnfyiqydpkdglykmmeerdgakfenivhnfkerqmmvsypkideddtwyn
    ltefvqmdkirkivrkdenqfsyvdssmttvqenelsssssdpahslnytvinfksreai
    rpghemedfldksyylntvmlqgifknssnyfgelqfaflnamffgnygsslqwhamiel
    icssatvpkhmldkldeilyyqiktlpeqysdillnervwniclyssfqknslhntekim
    enkypell
    

    Sequence, based on observed residues (ATOM records): (download)
    >5r09B (B:)
    mntvpftsapievtigidqysfnvkenqpfhgikdipighvhvihfqhadnssmrygywf
    dcrmgnfyiqydpkdglykmmeerdgakfenivhnfkerqmmvsypkideddtwynltef
    vqmdkirkivrkdenqfsyvdssmttvqenelsdpahslnytvinfksreairpghemed
    fldksyylntvmlqgifknssnyfgelqfaflnamffgnygsslqwhamielicssatvp
    khmldkldeilyyqiktlpeqysdillnervwniclyssfqknslhntekimenkypell