PDB entry 5qu9

View 5qu9 on RCSB PDB site
Description: PanDDA analysis group deposition of ground-state model of Kalirin/Rac1 screened against a customized urea fragment library by X-ray Crystallography at the XChem facility of Diamond Light Source beamline I04-1
Class: hydrolase/transferase
Keywords: SGC - Diamond I04-1 fragment screening, XChemExplorer, HYDROLASE-TRANSFERASE complex
Deposited on 2019-12-13, released 2020-01-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-01-29, with a file datestamp of 2020-01-24.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ras-related c3 botulinum toxin substrate 1
    Species: Homo sapiens [TaxId:9606]
    Gene: RAC1, TC25, MIG5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5qu9a_
  • Chain 'B':
    Compound: Kalirin
    Species: Homo sapiens [TaxId:9606]
    Gene: KALRN, DUET, DUO, HAPIP, TRAD
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60229 (2-End)
      • conflict (140)
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5qu9A (A:)
    smqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdta
    gqedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldl
    rddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
    

    Sequence, based on observed residues (ATOM records): (download)
    >5qu9A (A:)
    mqaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtag
    qedydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlr
    ddkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl
    

  • Chain 'B':
    No sequence available.