PDB entry 5qsg

View 5qsg on RCSB PDB site
Description: PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z2856434903
Class: transcription
Keywords: SGC - Diamond I04-1 fragment screening, PanDDA, XChemExplorer, TRANSCRIPTION
Deposited on 2019-05-25, released 2019-08-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-21, with a file datestamp of 2019-08-16.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-box transcription factor T
    Species: Homo sapiens [TaxId:9606]
    Gene: TBXT, T
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15178 (1-171)
      • engineered mutation (137)
    Domains in SCOPe 2.08: d5qsga_
  • Heterogens: O1A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5qsgA (A:)
gelrvgleeselwlrfkeltnemivtkngrrmfpvlkvnvsgldpnamysflldfvaadn
hrwkyvngewvpggkpepqapscvyihpdspnfgahwmkapvsfskvkltnklngggqim
lnslhkyeprihivrvgdpqrmitshcfpetqfiavtayqneeitalkikyn

    Sequence, based on observed residues (ATOM records): (download) 
    >5qsgA (A:)
elrvgleeselwlrfkeltnemivtkngrrmfpvlkvnvsgldpnamysflldfvaadnh
rwkyvngewvpggkpepqapscvyihpdspnfgahwmkapvsfskvkltnklngggqiml
nslhkyeprihivrvgdpqrmitshcfpetqfiavtayqneeitalkikyn