PDB entry 5qix

View 5qix on RCSB PDB site
Description: Covalent fragment group deposition -- Crystal Structure of OUTB2 in complex with PCM-0103007
Class: hydrolase/hydrolase inhibitor
Keywords: SGC - Diamond I04-1 fragment screening, XChemExplorer, PROTEASE OTUB2, DEUBIQUITINATING ENZYME OTUB2, hydrolase-hydrolase inhibitor complex
Deposited on 2018-08-10, released 2019-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.39 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin thioesterase OTUB2
    Species: Homo sapiens [TaxId:9606]
    Gene: OTUB2, C14orf137, OTB2, OTU2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96DC9 (0-224)
      • conflict (43)
    Domains in SCOPe 2.08: d5qixa_
  • Heterogens: J5V, EDO, UNL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5qixA (A:)
fnlisekcdilsilrdhpenriyrrkieelskrftairktkgdrncfyralgysylesll
gksreifkfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssllkvfndq
sasdhivqflrlltsafirnradffrhfideemdikdfcthevepmatecdhiqitalsq
alsialqveyvdemdtalnhhvfpeaatpsvyllyktshynilya

    Sequence, based on observed residues (ATOM records): (download) 
    >5qixA (A:)
fnlisekcdilsilrdhpenriyrrkieelskrftairktkgdrncfyralgysylesll
gksreifkfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssllkvfndq
sasdhivqflrlltsafirnradffrhfiemdikdfcthevepmatecdhiqitalsqal
sialqveyvdemdtalnhhvfpeaatpsvyllyktshynilya