PDB entry 5p9n
View 5p9n on RCSB PDB site
Description: humanized rat COMT in complex with 5-(4-fluorophenyl)-2,3-dihydroxy-N-[[3-[hydroxy-(1-methylindazol-5-yl)methyl]phenyl]methyl]benzamide at 1.17A
Class: transferase
Keywords: methyltransferase, neurotransmitter degradation, transferase
Deposited on
2016-10-19, released
2017-11-22
The last revision prior to the SCOPe 2.06 freeze date was dated
2017-11-22, with a file datestamp of
2017-11-17.
Experiment type: XRAY
Resolution: 1.17 Å
R-factor: N/A
AEROSPACI score: 0.67
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Catechol O-methyltransferase
Species: Rattus norvegicus [TaxId:10116]
Gene: COMT
Database cross-references and differences (RAF-indexed):
- Uniprot P22734
- engineered mutation (90)
- engineered mutation (94)
Domains in SCOPe 2.06: d5p9na_ - Heterogens: MG, CL, NHE, D1D, SO4, 7JE, 8JE, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5p9nA (A:)
mgdtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireysps
lvlelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasq
dlipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdfl
ayvrgsssfecthyssyleymkvvdglekaiyqgpsspdks
Sequence, based on observed residues (ATOM records): (download)
>5p9nA (A:)
dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssyleymkvvdglekaiyqgp