PDB entry 5p9j

View 5p9j on RCSB PDB site
Description: btk1 cocrystallized with ibrutinib
Class: transferase
Keywords: kinase, kinase-ligand complex, TRANSFERASE
Deposited on 2016-09-20, released 2017-05-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-21, with a file datestamp of 2018-02-16.
Experiment type: XRAY
Resolution: 1.08 Å
R-factor: N/A
AEROSPACI score: 0.75 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5p9ja_
  • Heterogens: 8E8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5p9jA (A:)
gknapstaglgygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsed
efieeakvmmnlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqlle
mckdvceameyleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfp
vrwsppevlmyskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrph
lasekvytimyscwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >5p9jA (A:)
sweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnls
heklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyle
skqflhrdlaarnclvndqgvvkvsdfglsryvlddeytgskfpvrwsppevlmyskfss
ksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimyscwhe
kaderptfkillsnildvmdees