PDB entry 5ohp

View 5ohp on RCSB PDB site
Description: Crystal structure of USP30 (C77A) in complex with Lys6-linked diubiquitin
Class: hydrolase
Keywords: DUB, Ubiquitin, USP, K6, HYDROLASE
Deposited on 2017-07-17, released 2017-09-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-15, with a file datestamp of 2017-11-10.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 30
    Species: Homo sapiens [TaxId:9606]
    Gene: usp30
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q70CQ3 (2-116)
      • engineered mutation (15)
      • linker (117-120)
    • Uniprot Q70CQ3 (121-261)
      • engineered mutation (252)
      • engineered mutation (254)
      • engineered mutation (257)
      • linker (262-264)
    • Uniprot Q70CQ3 (265-335)
    Domains in SCOPe 2.07: d5ohpa_
  • Chain 'B':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ohpb_
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Homo sapiens [TaxId:9606]
    Gene: UBB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ohpc_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5ohpA (A:)
    gpkglvpglvnlgntafmnsllqglsacpafirwleeftsqysrdqkeppshqylsltll
    hllkalscqevtddevldasclldvlrmyrwqissfeeqdahelfhvitsslederdgsg
    shwksqhpfhgrltsnmvckhcehqspvrfdtfdslslsipaatwghpltldhclhhfis
    sesvrdvvcdnctkieakgtlngekvehqrttfvkqlklgklpqclcihlqrlswsshgt
    plkrhehvqfnedlsmdeykyhsnastylfrlmavvvhhgdmhsghfvtyrrsppsarnp
    lstsnqwlwvsddtvrkaslqevlsssayllfyerv
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ohpA (A:)
    kglvpglvnlgntafmnsllqglsacpafirwleeftsqyshqylsltllhllkalscqe
    vtddevldasclldvlrmyrwqissfeeqdahelfhvitsslederdgsgshwksqhpfh
    grltsnmvckhcehqspvrfdtfdslslsipaatwghpltldhclhhfissesvrdvvcd
    nctkiehqrttfvkqlklgklpqclcihlqrlswsshgtplkrhehvqfnedlsmdeyky
    hsnastylfrlmavvvhhgdmhsghfvtyrrsppsarnplstsnqwlwvsddtvrkaslq
    evlsssayllfyerv
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >5ohpB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >5ohpC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

    Sequence, based on observed residues (ATOM records): (download)
    >5ohpC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlr