PDB entry 5obr
View 5obr on RCSB PDB site
Description: Aurora A kinase in complex with 2-(3-chloro-5-fluorophenyl)quinoline-4-carboxylic acid and JNJ-7706621
Class: cell cycle
Keywords: inhibitor, kinase, allostery, protein-protein interface, CELL CYCLE
Deposited on
2017-06-29, released
2017-08-09
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-01-24, with a file datestamp of
2018-01-19.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.18
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Aurora kinase A
Species: Homo sapiens [TaxId:9606]
Gene: AURKA, AIK, AIRK1, ARK1, AURA, AYK1, BTAK, IAK1, STK15, STK6
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d5obra_ - Heterogens: 9QT, SKE, MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>5obrA (A:)
gsmgskrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlr
reveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyite
lanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppe
miegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardl
isrllkhnpsqrpmlrevlehpwitansskps
Sequence, based on observed residues (ATOM records): (download)
>5obrA (A:)
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhgtldylppemiegrmhdekvdlwsl
gvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlr
evlehpwitansskp