PDB entry 5o22

View 5o22 on RCSB PDB site
Description: E. coli FolD in complex with carolacton
Class: oxidoreductase
Keywords: carolacton, FolD, natural product, inhibitor, oxidoreductase
Deposited on 2017-05-19, released 2018-02-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional protein folD
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: folD, ads, b0529, JW0518
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5o22a1, d5o22a2
  • Chain 'B':
    Compound: Bifunctional protein folD
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: folD, ads, b0529, JW0518
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24186 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.07: d5o22b1, d5o22b2, d5o22b3
  • Chain 'C':
    Compound: Bifunctional protein folD
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: folD, ads, b0529, JW0518
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5o22c1, d5o22c2
  • Chain 'D':
    Compound: Bifunctional protein folD
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: folD, ads, b0529, JW0518
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24186 (2-End)
      • expression tag (1)
    Domains in SCOPe 2.07: d5o22d1, d5o22d2, d5o22d3
  • Heterogens: C3R, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5o22A (A:)
mgaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnpasqiyvaskrkace
evgfvsrsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkd
vdgfhpynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmel
llagctttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengk
vvgdvvfedaakrasyitpvpggvgpmtvatlientlqacveyhdpqde

    Sequence, based on observed residues (ATOM records): (download) 
    >5o22A (A:)
aakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnyvaskrkaceevgfvsr
sydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkdvdgfhpy
nvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmelllagctt
tvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengkvvgdvvf
edaakrasyitpvpggvgpmtvatlientlqacveyhdpq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5o22B (B:)
mgaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnpasqiyvaskrkace
evgfvsrsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkd
vdgfhpynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmel
llagctttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengk
vvgdvvfedaakrasyitpvpggvgpmtvatlientlqacveyhdpqde

    Sequence, based on observed residues (ATOM records): (download) 
    >5o22B (B:)
gaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsniyvaskrkaceevgfv
srsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkdvdgfh
pynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmelllagc
tttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengkvvgdv
vfedaakrasyitpvpggvgpmtvatlientlqacveyhd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5o22C (C:)
mgaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnpasqiyvaskrkace
evgfvsrsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkd
vdgfhpynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmel
llagctttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengk
vvgdvvfedaakrasyitpvpggvgpmtvatlientlqacveyhdpqde

    Sequence, based on observed residues (ATOM records): (download) 
    >5o22C (C:)
aakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnpasqiyvaskrkaceev
gfvsrsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkdvd
gfhpynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmelll
agctttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengkvv
gdvvfedaakrasyitpvpggvgpmtvatlientlqacveyhdp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5o22D (D:)
mgaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgsnpasqiyvaskrkace
evgfvsrsydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkd
vdgfhpynvgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmel
llagctttvthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrlengk
vvgdvvfedaakrasyitpvpggvgpmtvatlientlqacveyhdpqde

    Sequence, based on observed residues (ATOM records): (download) 
    >5o22D (D:)
gaakiidgktiaqqvrsevaqkvqariaaglrapglavvlvgyvaskrkaceevgfvsrs
ydlpettseaellelidtlnadntidgilvqlplpagidnvkvlerihpdkdvdgfhpyn
vgrlcqraprlrpctprgivtllerynidtfglnavvigasnivgrpmsmelllagcttt
vthrftknlrhhvenadllivavgkpgfipgdwikegaividvginrvvgdvvfedaakr
asyitpvpggvgpmtvatlientlqacveyhdp