PDB entry 5o11

View 5o11 on RCSB PDB site
Description: Crystal structure of PIM1 kinase in complex with small-molecule inhibitor
Class: transferase
Keywords: kinase, CX-4945, PIM1, Transferase
Deposited on 2017-05-17, released 2017-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase pim-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIM1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5o11a_
  • Heterogens: 3NG, IMD, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5o11A (A:)
hhhhhhsqdpnsmkekeplesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdris
dwgelpngtrvpmevvllkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfite
rgalqeelarsffwqvleavrhchncgvlhrdikdenilidlnrgelklidfgsgallkd
tvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvff
rqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgpsk

    Sequence, based on observed residues (ATOM records): (download) 
    >5o11A (A:)
lesqyqvgpllgsggsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvllkk
vssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvleav
rhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppewiry
hryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwclalrp
sdrptfeeiqnhpwmqdvllpqetaeihlh