PDB entry 5nzz

View 5nzz on RCSB PDB site
Description: Crystal structure of phosphorylated p38aMAPK in complex with TAB1
Class: transferase
Keywords: MAPK activated phosphorylated P38 regulation, TRANSFERASE
Deposited on 2017-05-15, released 2018-05-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-30, with a file datestamp of 2018-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tgf-beta-activated kinase 1 and map3k7-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TAB1, MAP3K7IP1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: tgf-beta-activated kinase 1 and map3k7-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TAB1, MAP3K7IP1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: tgf-beta-activated kinase 1 and map3k7-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TAB1, MAP3K7IP1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: tgf-beta-activated kinase 1 and map3k7-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TAB1, MAP3K7IP1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Mitogen-activated protein kinase 14
    Species: Mus musculus [TaxId:10090]
    Gene: Mapk14, Crk1, Csbp1, Csbp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nzze_
  • Chain 'F':
    Compound: Mitogen-activated protein kinase 14
    Species: Mus musculus [TaxId:10090]
    Gene: Mapk14, Crk1, Csbp1, Csbp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nzzf_
  • Chain 'G':
    Compound: Mitogen-activated protein kinase 14
    Species: Mus musculus [TaxId:10090]
    Gene: Mapk14, Crk1, Csbp1, Csbp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nzzg_
  • Chain 'H':
    Compound: Mitogen-activated protein kinase 14
    Species: Mus musculus [TaxId:10090]
    Gene: Mapk14, Crk1, Csbp1, Csbp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nzzh_
  • Heterogens: NI, AGS, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5nzzE (E:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5nzzE (E:)
erptfyrqelnktiwevperyqnlspvgsvcaafdtktghrvavkklsrpfqsiihakrt
yrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvq
fliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwy
rapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellk
kissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayf
aqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >5nzzF (F:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5nzzF (F:)
rptfyrqelnktiwevperyqnlspvsvcaafdtktghrvavkklsrpfqsiihakrtyr
elrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvqfl
iyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwyra
peimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkki
ssesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaq
yhdpddepvadpydqsfesrdllidewksltydevisfvpppl

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5nzzG (G:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5nzzG (G:)
rptfyrqelnktiwevperyqnlspvgsvcaafdtktghrvavkklsrpfqsiihakrty
relrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvqf
liyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwyr
apeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkk
issesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfa
qyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5nzzH (H:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >5nzzH (H:)
rptfyrqelnktiwevperyqnlspsvcaafdtktghrvavkklsrpfqsiihakrtyre
lrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvqfli
yqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwyrap
eimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellksse
sarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhd
pepvadpydqsfesrdllidewksltydevisfvppp