PDB entry 5nwz

View 5nwz on RCSB PDB site
Description: fibroblast growth factor receptor 4 kinase domain (449-753) in complex with irreversible ligand cga159527
Class: hormone/growth factor
Keywords: HORMONE-GROWTH FACTOR complex
Deposited on 2017-05-09, released 2018-04-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nwza_
  • Chain 'B':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5nwzb_
  • Heterogens: 9CT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5nwzA (A:)
    gplvsldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlk
    dnasdkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarr
    ppgpdlspdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvm
    kiadfglargvhhidyykktsngrlpvkwmapealfdrvythqsdvwsfgillweiftlg
    gspypgipveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkv
    llavsee
    

    Sequence, based on observed residues (ATOM records): (download)
    >5nwzA (A:)
    lpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkdnasdkd
    ladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrppgpdlp
    lsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfglpvkwmapeal
    fdrvythqsdvwsfgillweiftlggspypgipveelfsllreghrmdrpphcppelygl
    mrecwhaapsqrptfkqlvealdkvllavse
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >5nwzB (B:)
    gplvsldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlk
    dnasdkdladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarr
    ppgpdlspdgprssegplsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvm
    kiadfglargvhhidyykktsngrlpvkwmapealfdrvythqsdvwsfgillweiftlg
    gspypgipveelfsllreghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkv
    llavsee
    

    Sequence, based on observed residues (ATOM records): (download)
    >5nwzB (B:)
    lpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkdnasdkd
    ladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrppplsfp
    vlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfgrlpvkwmapealfdr
    vythqsdvwsfgillweiftlggspypgipveelfsllreghrmdrpphcppelyglmre
    cwhaapsqrptfkqlvealdkvllavse