PDB entry 5ntk

View 5ntk on RCSB PDB site
Description: Structural states of RORgt: X-ray elucidation of molecular mechanisms and binding interactions for natural and synthetic compounds
Class: nuclear protein
Keywords: nuclear hormone receptor, ligand-binding domain, inverse agonist, NUCLEAR PROTEIN
Deposited on 2017-04-28, released 2017-06-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-19, with a file datestamp of 2017-07-14.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: RORC, NR1F3, RORG, RZRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449
      • engineered mutation (193)
    Domains in SCOPe 2.07: d5ntka_
  • Chain 'B':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: RORC, NR1F3, RORG, RZRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449
      • engineered mutation (193)
    Domains in SCOPe 2.07: d5ntkb_
  • Heterogens: 99N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ntkA (A:)
gpyaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwerca
hhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegk
yggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveq
lqynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhp

    Sequence, based on observed residues (ATOM records): (download) 
    >5ntkA (A:)
aslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahhl
teaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkygg
melfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlqy
nlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ntkB (B:)
gpyaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwerca
hhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegk
yggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveq
lqynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhp

    Sequence, based on observed residues (ATOM records): (download) 
    >5ntkB (B:)
aslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahhl
teaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkygg
melfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlqy
nlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhl