PDB entry 5nkb

View 5nkb on RCSB PDB site
Description: Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 4a
Class: transferase
Keywords: Inhibitor, Complex, Protein Tyrosine Kinase, transferase
Deposited on 2017-03-31, released 2017-06-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-A receptor 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHA2, ECK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5nkba_
  • Heterogens: 8ZT, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5nkbA (A:)
gdpnqavlkftteihpscvtrqkvigagefgevykgmlktssgkkevpvaiktlkagyte
kqrvdflgeagimgqfshhniirlegviskykpmmiiteymengaldkflrekdgefsvl
qlvgmlrgiaagmkylanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatytt
sggkipirwtapeaisyrkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgf
rlptpmdcpsaiyqlmmqcwqqerarrpkfadivsildklirapdslktladfdprvsir
lpstsg

    Sequence, based on observed residues (ATOM records): (download) 
    >5nkbA (A:)
tteihpscvtrqkvigagefgevykgmlkkevpvaiktlkagytekqrvdflgeagimgq
fshhniirlegviskykpmmiiteymengaldkflrekdgefsvlqlvgmlrgiaagmky
lanmnyvhrdlaarnilvnsnlvckvsdfglsrvleddpeatyttgkipirwtapeaisy
rkftsasdvwsfgivmwevmtygerpywelsnhevmkaindgfrlptpmdcpsaiyqlmm
qcwqqerarrpkfadivsildklirapdslktladfdprvsirlp