PDB entry 5nje

View 5nje on RCSB PDB site
Description: The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with Alpha-Bromo-3-Iodotoluene.
Class: transferase
Keywords: PLK1, PBD1, mitosis, small molecule, transferase
Deposited on 2017-03-28, released 2018-05-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-05-16, with a file datestamp of 2018-05-11.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5njea1, d5njea2
  • Heterogens: 8Z5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5njeA (A:)
    gahmdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyq
    lcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnym
    sehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcpl
    maavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas
    

    Sequence, based on observed residues (ATOM records): (download)
    >5njeA (A:)
    dchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdn
    svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
    lkaganitrlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekrd
    frtyrlslleeygcckelasrlryartmvdkllss