PDB entry 5nge

View 5nge on RCSB PDB site
Description: Crystal structure of USP7 in complex with the non-covalent inhibitor, FT671
Class: hydrolase
Keywords: DEUBIQUITINATION, Hydrolase
Deposited on 2017-03-17, released 2017-10-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ngea_
  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase 7
    Species: Homo sapiens [TaxId:9606]
    Gene: USP7, HAUSP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5ngeb_
  • Heterogens: 8WK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5ngeA (A:)
gskkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfy
elqhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfr
gkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehg
lqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdp
anyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddl
svrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqkrkerqe

    Sequence, based on observed residues (ATOM records): (download) 
    >5ngeA (A:)
gyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqhsd
kpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrgkmvsy
iqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqeaek
gvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpanyilh
avlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghctnaymlvyi
resklsevlqavtdhdipqqlverlqeekrieaqkrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5ngeB (B:)
gskkhtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfy
elqhsdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfr
gkmvsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehg
lqeaekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdp
anyilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddl
svrhctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaqkrkerqe

    Sequence, based on observed residues (ATOM records): (download) 
    >5ngeB (B:)
htgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelqh
sdkpvgtkkltksfgwetldsfmqhdvqelcrvlldnvenkmkgtcvegtipklfrgkmv
sysdrredyydiqlsikgkknifesfvdyvavekgvkfltlppvlhlqlmrfmydpqtdq
nikindrfefpeqlpldeflqktdpkdpanyilhavlvhsgdnhgghyvvylnpkgdgkw
ckfdddvvsrctkeeaiehnygghsvrhctnaymlvyiresklsevlqavtdhdipqqlv
erlqeekrieaqk