PDB entry 5net

View 5net on RCSB PDB site
Description: Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose A.
Class: virus
Keywords: Foot and Mouth Disease Virus, FMDV, virus, OpanAsia, virus-receptor, complex
Deposited on 2017-03-11, released 2017-06-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-10.
Experiment type: EM
Resolution: 8.6 Å
R-factor: N/A
AEROSPACI score: -0.03 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: O1 Manisa VP1
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5net1_
  • Chain '2':
    Compound: O1 Manisa VP2
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q6PMW3 (Start-217)
      • conflict (92)
  • Chain '3':
    Compound: O1 Manisa VP3
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q80B23 (0-219)
      • conflict (55)
      • conflict (167)
    Domains in SCOPe 2.08: d5net3_
  • Chain '4':
    Compound: O1 Manisa VP4
    Species: Foot-and-mouth disease virus [TaxId:12110]
    Database cross-references and differences (RAF-indexed):
  • Chain 'A':
    Compound: Integrin alpha-V
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGAV, MSK8, VNRA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06756 (0-593)
      • conflict (399)
    Domains in SCOPe 2.08: d5neta1, d5neta2
  • Chain 'B':
    Compound: integrin beta-6
    Species: Homo sapiens [TaxId:9606]
    Gene: ITGB6
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18564 (0-469)
      • conflict (265)
      • conflict (447)
  • Heterogens: MAN, NAG, CA

PDB Chain Sequences:

  • Chain '1':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5net1 (1:)
ttsagesadpvtatvenyggetqvqrrqhtdvsfildrfvkvtpkdqinvldlmqtpaht
lvgallrtatyyfadlevavkhegnltwvpngapeaaldnttnptayhkapltrlalpyt
aphrvlatvyngnskygdgtvanvrgdlqvlaqkaaralptsfnygaikatrvtellyrm
kraetycprpllaihpdqarhkqkivap

  • Chain '2':
    No sequence available.

  • Chain '3':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5net3 (3:)
gifpvacsdgygglvttdpktadpaygkvfnpprnmlpgrftnfldvaeacptflrfegd
vpyvttktdsdrvlaqfdlslaakhmsntflaglaqyytqysgtinlhfmftgptdakar
ymiayappgmeppktpeaaahcihaewdtglnskftfsipylsaadytytasdvaettnv
qgwvclfqithgkadgdalvvlasagkdfelrlpvdartq

  • Chain '4':
    No sequence available.

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5netA (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahill

    Sequence, based on observed residues (ATOM records): (download) 
    >5netA (A:)
fnldvdspaeysgpegsyfgfavdffvpssrmfllvgapkanttqpgiveggqvlkcdws
strrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkqer
epvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywqgq
lisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfvsg
vpraartlgmvyiydgknmssynftgeqmaayfgfsvaatdingddyadvfigaplfmdr
gsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiaiaap
yggedkkgivyifngrstglnavpsqilegqwaarscppsfgysmkgatdidkngypdli
vgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclkadg
kgvlprklnfqvellldklkgairralflysrspshsknmtisrgglmqceeliaylrde
sefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahill

  • Chain 'B':
    No sequence available.