PDB entry 5nei

View 5nei on RCSB PDB site
Description: The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with JES107
Class: transferase
Keywords: PLK1, PBD1, mitosis, small molecule, transferase
Deposited on 2017-03-10, released 2018-02-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-21, with a file datestamp of 2018-02-16.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5neia1, d5neia2
  • Heterogens: 8VB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5neiA (A:)
gahmdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyq
lcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnym
sehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcpl
maavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas

    Sequence, based on observed residues (ATOM records): (download) 
    >5neiA (A:)
dchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdn
svgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehl
lkaganitrlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekrd
frtyrlslleeygcckelasrlryartmvdkllssr