PDB entry 5n2k

View 5n2k on RCSB PDB site
Description: Structure of unbound Briakinumab FAb
Class: immune system
Keywords: antagonist, antibody, extracellular region, Immune system
Deposited on 2017-02-07, released 2018-01-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2ka1, d5n2ka2
  • Chain 'B':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'C':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2kc1, d5n2kc2
  • Chain 'D':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'E':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2ke1, d5n2ke2
  • Chain 'F':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'G':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2kg1, d5n2kg2
  • Chain 'H':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'I':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2ki1, d5n2ki2
  • Chain 'J':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'K':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2kk1, d5n2kk2
  • Chain 'L':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'M':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2km1, d5n2km2
  • Chain 'N':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Chain 'O':
    Compound: Briakinumab FAb light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
    Domains in SCOPe 2.08: d5n2ko1, d5n2ko2
  • Chain 'P':
    Compound: Briakinumab FAb heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 5N2K
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5n2kA (A:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kA (A:)
qsvltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptec

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5n2kC (C:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kC (C:)
svltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvpd
rfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvaptec

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >5n2kE (E:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kE (E:)
qsvltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >5n2kG (G:)
mgilpspgmpallslvsllsvllmgcvaesvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kG (G:)
esvltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvap

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >5n2kI (I:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kI (I:)
qsvltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >5n2kK (K:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kK (K:)
svltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvpd
rfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvapte

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >5n2kM (M:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kM (M:)
svltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvpd
rfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvap

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    Sequence, based on SEQRES records: (download) 
    >5n2kO (O:)
mgilpspgmpallslvsllsvllmgcvaqsvltqppsvsgapgqrvtiscsgsrsnigsn
tvkwyqqlpgtapklliyyndqrpsgvpdrfsgsksgtsaslaitglqaedeadyycqsy
drythpallfgtgtkvtvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtva
wkadsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektva
ptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2kO (O:)
qsvltqppsvsgapgqrvtiscsgsrsnigsntvkwyqqlpgtapklliyyndqrpsgvp
drfsgsksgtsaslaitglqaedeadyycqsydrythpallfgtgtkvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvvetttpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvap

  • Chain 'P':
    No sequence available.