PDB entry 5n2d

View 5n2d on RCSB PDB site
Description: Structure of PD-L1/small-molecule inhibitor complex
Class: cell cycle
Keywords: PD-L1, PD-1, small-molecule inhibitor, cell cycle
Deposited on 2017-02-07, released 2017-06-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (Start-132)
      • expression tag (133-140)
    Domains in SCOPe 2.08: d5n2da1, d5n2da2
  • Chain 'B':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (Start-132)
      • expression tag (133-139)
    Domains in SCOPe 2.08: d5n2db1, d5n2db2
  • Chain 'C':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (Start-132)
      • expression tag (133-142)
    Domains in SCOPe 2.08: d5n2dc1, d5n2dc2
  • Chain 'D':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (Start-132)
      • expression tag (133-139)
    Domains in SCOPe 2.08: d5n2dd1, d5n2dd2
  • Heterogens: 8J8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5n2dA (A:)
rifavfifmtywhllnaftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemed
kniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisygga
dykritvkvnapyaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2dA (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5n2dB (B:)
rifavfifmtywhllnaftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemed
kniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisygga
dykritvkvnapyaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2dB (B:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehh

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >5n2dC (C:)
rifavfifmtywhllnaftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemed
kniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisygga
dykritvkvnapyaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2dC (C:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehhhhh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >5n2dD (D:)
rifavfifmtywhllnaftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemed
kniiqfvhgeedlkvqhssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisygga
dykritvkvnapyaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5n2dD (D:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlkvq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lehh