PDB entry 5n0h

View 5n0h on RCSB PDB site
Description: Crystal structure of NDM-1 in complex with hydrolyzed meropenem - new refinement
Class: hydrolase/antibiotic
Keywords: HYDROLASE-ANTIBIOTIC complex, metallo-beta-lactamase, NDM-1
Deposited on 2017-02-03, released 2017-04-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-13, with a file datestamp of 2017-12-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metallo-beta-lactamase type 2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaNDM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot C7C422 (Start-241)
      • expression tag (242-244)
    Domains in SCOPe 2.07: d5n0ha1, d5n0ha2
  • Chain 'B':
    Compound: Metallo-beta-lactamase type 2
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: blaNDM-1
    Database cross-references and differences (RAF-indexed):
    • Uniprot C7C422 (Start-241)
      • expression tag (242-243)
    Domains in SCOPe 2.07: d5n0hb1, d5n0hb2
  • Heterogens: 8YL, ZN, GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5n0hA (A:)
geirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlv
vdtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnql
apqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggc
likdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadk
lrklx

    Sequence, based on observed residues (ATOM records): (download) 
    >5n0hA (A:)
tgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlvvdtawtddqtaq
ilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnqlapqegmvaaqhs
ltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggclikdskakslgn
lgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadklrklx

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5n0hB (B:)
geirptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlv
vdtawtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnql
apqegmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggc
likdskakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadk
lrklx

    Sequence, based on observed residues (ATOM records): (download) 
    >5n0hB (B:)
ptigqqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlvvdta
wtddqtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnqlapqe
gmvaaqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggclikd
skakslgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadklrkl