PDB entry 5mrk

View 5mrk on RCSB PDB site
Description: Structural basis of Zika virus methyltransferase inhibition by sinefungin
Class: transferase
Keywords: zika, virus, methyltransferase, sinefungin, transferase
Deposited on 2016-12-23, released 2017-01-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-06-28, with a file datestamp of 2017-06-23.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Methyltransferase
    Species: Zika virus (strain Mr 766) [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5mrka_
  • Chain 'B':
    Compound: Methyltransferase
    Species: Zika virus (strain Mr 766) [TaxId:64320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5mrkb_
  • Heterogens: SFG, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5mrkA (A:)
sgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepmlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtr

    Sequence, based on observed residues (ATOM records): (download) 
    >5mrkA (A:)
getlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrw
lvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepmlvqsygwniv
rlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvl
cpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrm
dgprrpvkyeedvnlgsgtr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5mrkB (B:)
sgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepmlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtr

    Sequence, based on observed residues (ATOM records): (download) 
    >5mrkB (B:)
getlgekwkarlnqmsalefysykksgitevcrhavsrgsaklrwlvergylqpygkvid
lgcgrggwsyyaatirkvqevkgytkggpgheepmlvqsygwnivrlksgvdvfhmaaep
cdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlcpytstmmetlerlq
rryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmdgprrpvkyeedvnl
gsgtr