PDB entry 5mo9

View 5mo9 on RCSB PDB site
Description: Structure of human TrkB receptor ligand binding domain in complex with the Fab frgment of antibody AB20
Class: immune system
Keywords: Trk receptor, antibody, antigen, complex, immune system
Deposited on 2016-12-14, released 2017-08-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-03, with a file datestamp of 2019-03-29.
Experiment type: XRAY
Resolution: 2.59 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: AB20 Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MO9 (0-End)
    Domains in SCOPe 2.08: d5mo9h1, d5mo9h2
  • Chain 'L':
    Compound: AB20 Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 5MO9 (0-218)
    Domains in SCOPe 2.08: d5mo9l1, d5mo9l2
  • Chain 'X':
    Compound: bdnf/nt-3 growth factors receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NTRK2, TRKB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d5mo9x_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >5mo9H (H:)
qvqlqqsgaelvrpgasvtlsckasgytftdyemhwvkqtpvhglewigtidpetagtay
nqkfkgkailtagkssstaymelrsltsedsavyyctgvttwfaywgqgtlvtvsaastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >5mo9H (H:)
qvqlqqsgaelvrpgasvtlsckasgytftdyemhwvkqtpvhglewigtidpetagtay
nqkfkgkailtagkssstaymelrsltsedsavyyctgvttwfaywgqgtlvtvsaastk
gpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvpssslgtqtyicnvnhkpsntkvdkkvepk

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >5mo9L (L:)
dvvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspnlliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqgthvpytfgggtkleikrtvaapsv
fifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysl
sstltlskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >5mo9X (X:)
mgsvnltvhfaptitflesptsdhhwcipftvkgnpkpalqwfyngailneskyictkih
vtnhteyhgclqldnpthmnngdytliakneygkdekqisahfmgwpgiddganpnypdv
iyedygtaandigdttnrsneipstdvtdkt

    Sequence, based on observed residues (ATOM records): (download) 
    >5mo9X (X:)
vhfaptitflesptsdhhwcipftvkgnpkpalqwfyngailneskyictkihvtnhtey
hgclqldnpthmnngdytliakneygkdekqisahfmgwpgi