PDB entry 5mky

View 5mky on RCSB PDB site
Description: BROMODOMAIN OF HUMAN BRD9 WITH 4-chloro-2-methyl-5-((2-methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)amino)pyridazin-3(2H)-one
Class: transcription
Keywords: brd9, inhibitor, histone, epigenetic reader, bromodomain, transcription
Deposited on 2016-12-05, released 2017-12-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-12-20, with a file datestamp of 2017-12-15.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 9
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD9, UNQ3040/PRO9856
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5mkya_
  • Heterogens: I0D, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5mkyA (A:)
gaenestpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkiva
neyksvtefkadfklmcdnamtynrpdtvyyklakkilhagfkmms

    Sequence, based on observed residues (ATOM records): (download) 
    >5mkyA (A:)
stpiqqllehflrqlqrkdphgffafpvtdaiapgysmiikhpmdfgtmkdkivaneyks
vtefkadfklmcdnamtynrpdtvyyklakkilhagfkmms